Top 80+ Solved General Physiology MCQ Questions Answer

a. provide motor supply to intrafusal muscle fibres

b. are usually the first fibres affected by local anaesthetics

c. are 12-20umol in diameter

d. are unmyelinated

e. provide pre-ganglionic autonomic supply

a. movement across an impermeable membrane occurs due to an osmotic gradient

b. equilibrium potential can be determined using the Nernst equation

c. movement across the capillary wall is not affected by the Donnan effect

d. valency determines osmotic effect in an ideal solution

e. forms of weak acids cross cell membranes easily

a. open ion channels in cell membrane

b. act via cytoplasmic or nuclear receptors

c. increase intracellular cAMP

d. increase tyrosine kinase activity of transmembrane receptors

e. act via a serpentine receptor

a. develop tetany only at very high stimulation frequencies

b. develop less tension when stretched due to decreased actin-myosin overlap

c. can derive only 5% of basal caloric requirement from fat

d. have a T-system located at the A-I junctions

e. remain absolutely refractory until the membrane potential repolarises to - 50mV

a. minimally filters protein, so plasma protein concentration is not altered

b. are supplied by an extensive anastomotic arterial network

c. lie distal to the juxtaglomerular apparatus

d. each receive approximately 20-25% of resting cardiac output

e. do not filter appreciable albumin since membrane pores are too small

a. absorbs most of the filtered sodium ions in the presence of aldosterone

b. absorbs glucose in the normal state

c. absorbs most of the filtered water in the presence of ADH

d. secretes hydrogen via secondary active transport

e. is almost entirely impermeable to urea

a. 25-hydroxycholecalciferol is converted to 1,25-dihydroxycholecalciferol in the distal convoluted tubule of the kidney

b. 1,25-dihydroxycholecalciferol receptors can be found in skin

c. when calcium levels are high, 24,25-dihydroxycholecalciferol levels are also high

d. transport in plasma is by binding to haemoglobin

e. formation of 25-hydroxycholecalciferol is tightly regulated

a. NH4 + is formed by reductive deamination of amino acids

b. most of the body’s urea is formed in the kidney

c. phosphorylcreatine is formed in the liver

d. creatinuria occurs normally in children

e. purines and pyrimidines are mainly sourced from dietary intake

a. 4.0 + 0 0

b. 6.2 2+ 4+ 0

c. 1.6 0 0 4+

d. 6.4 0 0 0

e. 5.0 0 0 3+

a. greater constriction of efferent than afferent arterioles

b. greater constriction of afferent than efferent arterioles

c. constriction of afferent arterioles only

d. constriction of efferent arterioles only

e. has no effect on arteriolar constriction

a. the GFR increases when flow through the distal tubule increases

b. the macula densa on the afferent arteriole is the sensor

c. the afferent arteriole is constricted by thromboxane A2

d. it is designed to maintain Na+ reabsorption

e. it does not operate in individual nephrons

a. 2ml/min

b. 10ml/min

c. 20ml/min

d. 200ml/min

e. clearance cannot be determined from the information given

a. Na is co-transported out of the tubule with glucose

b. Na is actively transported into the intercellular spaces by Na-K ATPase

c. the cells are characterised by a brush border and tight junctions

d. vasopressin increases the permeability to water by causing the rapid insertion of water channels into the luminal membrane

e. water moves passively out of the tubule along osmotic gradients

a. aldosterone increases K reabsorption from the distal tubule

b. angiotensin II increases H+ secretion from the proximal tubules

c. ADH increases water reabsorption in the proximal tubule

d. atrial naturetic peptide decreases Na+ reabsorption from the proximal tubules

e. parathyroid hormone increases phosphate reabsorption

a. relatively permeable to water

b. relatively impermeable to Na+

c. permeable to both water and Na+

d. relatively impermeable to water

e. relatively impermeable to both water and Na+