Top 80+ Solved General Physiology MCQ Questions Answer
Q. Serotonin is noted in all but:
a. sexual behaviour
b. obesity
c. platelet aggregation
d. mood
e. vomiting
Q. With respect to the ascending pathways of sensation within the spinal cord:
a. the ??? columns connect with the medial branches (crosses midline)
b. the central spinothalamic tract carries pain/temp fibres
c. the lateral spinothalamic tract has small fibres medially
d. gracile fasiculatus contains fibres from thoracic and cervical nerves
e. proprioception is transmitted in the lateral spinothalamic tract
Q. Which of the following decreases basal metabolic rate?
a. recent ingestion of food
b. stress
c. increased thyroid hormones
d. sleep
e. lactation
Q. Which of the following is an example of a low energy phosphate compound:
a. creatine phosphate
b. UTP
c. acetyl CoA
d. glucose-6 phosphate
e. ATP
Q. Creatinuria occurs in measurable amounts in all but:
a. women during and after pregnancy and occasionally in non-pregnant women
b. normal men
c. starvation
d. thyrotoxicosis
e. poorly controlled diabetes mellitus
Q. Plasma lipids and lipid transport:
a. apoprotein B48 occurs in VLDL
b. apoprotein B166 and apoprotein C occurs in chylomicrons
c. lecithin cholesterol acyltrasferase is responsible for transferring cholesterol esters from HDL to…
d. chylomicron remnants travel from the intestine within lymphatic fluid in the thoracic duct
e. one half of all LDL molecules is taken up by macrophages and other cells by means other than the LDL receptor
Q. Adrenal insufficiency may cause all but which of the following?
a. inability to excrete a water load
b. personality changes
c. sodium loss with circulatory insufficiency
d. hypoglycaemia in the presence of fasting
e. leukocytosis
Q. Hyperaldosteronism:
a. causes low plasmic Na+ and high H+
b. retains acid H+ ions and can cause acidosis
c. doesn’t cause oedema due to the escape phenomenon
d. may cause hypocalcaemic nephropathy
e. may be caused by high sodium intake
Q. Bone:
a. osteoblasts are multinucleate
b. osteoclasts attach to bone via integins
c. compact bone makes up 60% of a long bone
d. osteoblasts secrete large quantities of type IV collagen and other bone matrix proteins
e. oestrogens inhibit osteoblasts and stimulate osteoclasts
Q. Functional anatomy of the kidney – which is TRUE?
a. 5 million nephrons in each human kidney
b. pores in terestrated kidneys are 170-190nm in diameter
c. mesengial cells are located between the basal lumina and podocytes
d. glomerular membrane permits passage of small (???) neutral substances
e. proximal tubule is 100nm long
Q. Functional anatomy of the kidney – which is FALSE?
a. total length of the nephrons ranges from 45-65mm
b. the macula densa is ??? tubular epithelium of the collecting duct
c. juxtaglomerular cells are found in the walls of the different arteriole
d. intercolated cells are involved in acid secretion and bicarbonate transport
e. total glomerular capillary endothelium across which filtration occurs, is 0.8m2
Q. Regulation of renal blood flow – which is FALSE?
a. angiotensin II constricts the afferent arteriole and efferent arteriole
b. noradrenaline constricts intertubular arteries and afferent arterioles
c. dopamine causes vasodilation in renal vessels and natriuresis
d. ACh – renal vasodilation
e. prostaglandins increase blood flow to the cortex and decrease it in the medulla
Q. All but which of the following cause contraction of the mesengial cells?
a. endothelins
b. angiotensin II
c. ADH
d. noradrenaline
e. cAMP
Q. All but which of the following are involved in the movement of Na+/Cl- across the apical membrane of the proximal tubules?
a. Na+ / 2Cl- / K+ co-transporter (CT)
b. Na+/ glucose CT
c. Na+/P??? CT
d. Cl- / base exchanges
e. Na+ / H+ exchanges