Top 80+ Solved Metabolism and Endocrinology MCQ Questions Answer
Q. Nucleotide breakdown releases purines and pyrimidines. Which of the following is NOT their subsequent fate?
a. re-used to form nucleosides, nucleotides and nucleic acids
b. excreted unchanged in urine
c. directly enter the urea cycle
d. pyrimidines are catabolised to carbon dioxide and ammonia
e. purines are catabolised to uric acid
Q. Which of the following is NOT a purine?
a. adenine
b. cytosine
c. guanine
d. hypoxanthine
e. xanthine
Q. Creatinine appears in the urine in significant amounts in all of the following EXCEPT:
a. normal men
b. thyrotoxicosis
c. post-partum
d. poorly controlled diabetes mellitus
e. children
Q. Regarding free fatty acids, which statement is INCORRECT?
a. circulate in plasma bound to globulin
b. they are the major source of energy for cardiac muscle
c. combine with glycerol to form the triglyceride of neutral fat
d. contain an even number of carbon atoms
e. require linkage to carnitine in order to cross mitochondrial membranes prior to oxidation
Q. Which amino acid is NOT ketogenic (ie CAN’T be converted into acetoacetate)?
a. leucine
b. isoleucine
c. phenylalanine
d. tyrosine
e. proline
Q. Regarding cholesterol, which statement is INCORRECT?
a. dietary cholesterol is absorbed in the intestine and incorporated into chylomicrons formed in the mucosa
b. about 20% is in the plasma, with the remainder intracellular
c. negatively feeds back on its synthetic pathway
d. most hepatic synthesised cholesterol is incorporated into VLDL
e. thyroid hormones decrease the plasma cholesterol level
Q. Which lipoprotein contains the GREATEST proportion of triglyceride?
a. VLDL
b. IDL
c. chylomicrons
d. LDL
e. HDL
Q. Basal metabolic rate is GREATER in all of the following circumstances EXCEPT:
a. children compared with adults
b. Caucasians compared with Chinese and Indians
c. females compared with males
d. anxiety compared with depression
e. feeding compared with starvation
Q. Which lipoprotein contains the GREATEST proportion of cholesterol and cholesterolesters?
a. VLDL
b. IDL
c. chylomicrons
d. LDL
e. HDL
Q. What is the basal metabolic rate of an average sized man per day?
a. 1000 Kcal
b. 2000 Kcal
c. 3000 Kcal
d. 4000 Kcal
e. 5000 Kcal
Q. Which lipoprotein contains the GREATEST proportion of protein?
a. VLDL
b. IDL
c. chylomicrons
d. LDL
e. HDL
Q. What is the most important factor affecting metabolic rate?
a. muscular exertion
b. recent ingestion of food
c. high or low environmental temperature
d. height, weight and surface area
e. sex
Q. Which of the following are NON ESSENTIAL amino acids?
a. valine
b. leucine
c. isoleucine
d. cysteine
e. methionine