Top 80+ Solved Metabolism and Endocrinology MCQ Questions Answer
Q. Which of the following hormones does NOT increase the hepatic output of glucose?
a. growth hormone
b. adrenaline
c. glucagon
d. noradrenaline
e. cortisol
Q. Regarding the action of insulin on adipose tissue, which of the following isINCORRECT?
a. it induces lipoprotein lipase which actively hydrolyses triglyceride from circulating lipoproteins
b. it reduces circulating free fatty acids
c. it promotes triglyceride storage in adipocytes
d. it directly inhibits intracellular lipase
e. its effects appear to involve phosphorylation of lipases
Q. Which of the following tissues possess FEW thyroid hormone receptors?
a. liver
b. testis
c. kidney
d. heart
e. skeletal muscle
Q. Which glucose transporter is responsible for insulin-mediated glucose uptake instriated muscle and adipose tissue?
a. glut 1
b. glut 2
c. glut 3
d. glut 4
e. glut 5
Q. Where are the receptors located by which thyroid hormones mediate most of theireffects?
a. cell membrane
b. outer mitochondrial membrane
c. nuclear chromatin
d. inner mitochondrial membrane
e. cytoplasm
Q. Regarding the action of insulin in skeletal muscle, which of the following isINCORRECT?
a. it decreases protein catabolism
b. it induces glucogen synthase
c. it decreases ketone uptake
d. it increases amino acid uptake
e. it decreases the release of gluconeogenic amino acids
Q. Which thyroid hormone possesses the GREATEST biological activity?
a. T4
b. DIT
c. MIT
d. T3
e. RT3
Q. Which glucose transporter is responsible for the facilitated diffusion of glucose intopancreatic B cells?
a. glut 1
b. glut 2
c. glut 3
d. glut 4
e. glut 5
Q. Regarding the effects of thyroid hormones, which of the following does NOT occur?
a. it increases metabolic rate
b. it directly stimulates sodium-potassium ATPase
c. it increases protein and fat catabolism
d. it increases body temperature
e. it increases cerebral oxygen consumption
Q. Regarding the action of insulin on the liver, which of the following is INCORRECT?
a. it increases gluconeogenesis
b. it decreases glycogenolysis
c. it increases synthesis of triglyceride and VLDL
d. it decreases cyclic AMP
e. it increases phosphate uptake
Q. Which statement regarding the thyroid gland and its hormones is INCORRECT?
a. thyroid hyperactivity is associated with an increase in plasma catecholamines
b. iodide trapping by thyroid cells is an active process
c. thyroid hormones enter cells by diffusion across the cell membrane
d. thyroid hormones cause an increase in 2,3 - DPG
e. thyroid hormones increase growth hormone secretion
Q. Regarding the secretion of insulin, which statement is INCORRECT?
a. insulin is not required for glucose to enter pancreatic B cells
b. it involves closure of ATP-sensitive potassium channels
c. it is a biphasic process involving two pools of insulin
d. it involves opening of voltage-sensitive calcium channels
e. glucose enters pancreatic B cells by combining with glut 4
Q. Which of the following do NOT increase TSH secretion?
a. TRH
b. glucocorticoids
c. infants exposed to cold temperature
d. acute psychosis
e. night time
Q. Which of the following does NOT inhibit insulin secretion?
a. somatostatin
b. atropine
c. propranolol
d. gastrin
e. phenytoin