Top 350+ Solved Biopharmaceutics and Pharmacokinetics MCQ Questions Answer
Q. Which of the following is the half life of zero order reaction?
a. t1/2 = A0 /2k
b. t1/2 = 0.693/2k
c. t1/2 = A0 /2
d. t1/2 = 2k/ A0
Q. The unit of k for zero order reaction is
a. moles/litre/second
b. moles
c. moles/second
d. moles/litre
Q. Which of the following is the half life of first order reaction?
a. t1/2 = A0 / 2k
b. t1/2 = 0.693 / 2k
c. tl/2 = 2k
d. tl/2 = 0.693 / k
Q. Which of the following is not a pharmacokinetic parameters that describe the plasma level time curve?
a. tmax
b. cmax
c. Area under Curve
d. Minimum Effective Concentration
Q. The drug concentration between Minimum Effective Concentration and Maximum Safe Concentrationis called
a. Therapeutic range
b. Area under curve
c. Peak response
d. Pharmacological response
Q. tmax indicates
a. drug absorption rate
b. drug elimination rate
c. drug distribution rate
d. drug metabolism rate
Q. What Will be the approximate Tmax of a drug exhibiting Ka of 2 hr-1 and K of 0.2 hr-1 ?
a. 1.2 hr
b. 2.4 hr
c. 4.8 hr
d. 2.0 hr
Q. A drug solution has half life of 21 days. Assuming that drug undergoes first order kinetics, how long will it take for the potency to drop to 90% of initial potency?
a. 3.2 days
b. 9.6 days
c. 16 days
d. 6.2 days
Q. A suspension shows zero-order kinetic with a rate constant 2mg/ml.month. The dose of suspension is 20mg/ml. The biological half life of the above dosage form is
a. 5 months
b. 1 month
c. 3 months
d. 2 months
Q. Drug showing zero order kinetic of elimination
a. Are more common than those showing first order kinetic
b. Show plot of drug concentration vs time (linear Plot)
c. Decrease in concentration exponentially with time
d. Have half life independent of dose
Q. Which one is irrational statement for first order kinetics?
a. Half life is a function of concentration of reactants
b. Reaction rate is not a function of concentration of reactants
c. Both a & b
d. All of these
Q. T % (Half life time) of a drug can determine all of the following except
a. Closing interval
b. Therapeutic dose
c. Elimination time
d. Steady plasma concentration
Q. The area under serum concentration time curve of drug represents
a. The biological half life of the drug
b. Amount of drug biotransformed
c. The amount of drug absorbed
d. The amount of drug excreted in urine
Q. Under non compartment analysis the following formula is used for calculation
a. MRT = AUMC / AUC
b. AUMC = MRT / AUC
c. MRT = AUC / AUMC
d. AUC = AUMC / MRT