Top 350+ Solved Biopharmaceutics and Pharmacokinetics MCQ Questions Answer
Q. A hydrophilic medicinal agent has
a. Low ability to penetrate through the cell membrane lipids
b. Easy permeation through the blood-brain barrier
c. Penetrate through membranes by means of endocytosis
d. High reabsorption in renal tubules
Q. Biological barriers include all except:
a. Renal tubules
b. Cell membranes
c. Capillary walls
d. Placenta
Q. If a CNS drug is extensively ionized at pH of blood it will
a. Penetrate the blood brain barrier slowly
b. Penetrate the blood brain barrier rapidly
c. Not penetrate blood brain barrier
d. Be eliminated slowly
Q. The rate of drug transport across a cell membrane by lipid diffusion depends on all of the followingexcept
a. Drug size (diffusion constant)
b. Surface area of absorption
c. Lipid partition coefficient
d. Density of tr
Q. The formula to calculate half life (t1/2) is
a. 0.693 *Vd / C1
b. 0.693 *Cl / Vd
c. 0.693 / Cl * Vd
d. 0.693 / Cl
Q. The procedure of transporting a drug from the bloodstream to tissues is called as
a. Absorption
b. Dissolution
c. Distribution
d. Elimination
Q. …………..it represents the degree to which a drug is distributed in body tissue rather than
a. Volume of distribution (YD)
b. Effect of distribution
c. Area of distribution
d. None of the above
Q. It is defined as the distribution of a drug between plasma and the rest of the body after oral orparenteral dosing.
a. Volume of distribution (VD)
b. Apparent volume of drug distribution
c. Phagocytosis
d. None of the above
Q. The drugs having molecular size …………..easily cross capillary membrane.
a. <500-600d
b. < 100-200 d
c. <300-600d
d. <90M600d
Q. The concentration of drug in blood or plasma will be comparatively in the GI tract.
a. High
b. Low
c. Very High
d. Very Low
Q. Fat is act as reservoir for……………………… Drugs
a. Highly water soluble
b. Lower lipid soluble
c. Highly lipid soluble
d. Lower lipid soluble
Q. Displacement is significant when, the displaced drug is more than protein bound.
a. 50%
b. 95%
c. 10%
d. 1%
Q. If distribution of drug is slower than process of biotransformation and elimination
a. It will cause high blood level of drug
b. It will cause low blood level of drug
c. Cause failure to attain diffusion equilibrium
d. None of the above