Top 150+ Solved Medicinal Chemistry 1 MCQ Questions Answer
Q. The most important physicochemical properties affecting drug action a) Partition coefficient b) Solubility c) Acid base properties d) Chemical bonding e) Chelation f) Surface activity
a. All of the above
b. A and B both
c. D and E both
d. C and F both
Q. In QSAR, study of medicinal chemistry Q stands for
a. Qualitative
b. Quantitative
c. Both
d. Quantam
Q. Dimercaprol is a chelating agent used in the treatment of
a. Arsenic poisoning
b. Lead poisoning
c. Iron poisoning
d. Vanadium poisoning
Q. The non-polar compound dispersed
a. By forming hydrogen bonding
b. By interacting with lipid
c. By forming drug receptor complex
d. by forming hydrophilic bond
Q. pka is a parameter which indicates the
a. Strength of drug as acid base reaction in water
b. Aqueous phase in phosphate buffer
c. Hydrophilic and lyphophilic character
d. All of the above
Q. Bioisoterism is the process of
a. Replacement similar group
b. Replacement similar valence group
c. Replacement similar mass no. group
d. Addition of group having different mass no.
Q. A drug like phenytoin & barbiturate when pka is larger than 7 is
a. Ionised at all pH
b. unionised at pH
c. Ionised at pH 8
d. Unionised at pH 6
Q. A drug where pka is 7 & unionised at all pH it is
a. Weak acidic
b. Very weak acidic
c. Weak basic
d. Very weak basic
Q. Dissolution & pka helps in drug
a. ionization & solubility
b. dissociation & transportation
c. Dissociation & solubility
d. None of these
Q. Bioisosteres are similar in their
a. Physical character
b. Chemical character
c. Both character a & b
d. Biochemical character
Q. A molecule having 3 chiral centre carbon it has
a. 4 set of diasters
b. 9 set of enantiomers
c. 6 set of monomers
d. 9 set of diasters
Q. Which of the following is odd one regarding drug-receptor interaction
a. Hydrogen bonding
b. Electrostatic
c. Weak Wander wall Force
d. Dipole- induced dipole interaction