Top 150+ Solved Medicinal Chemistry 1 MCQ Questions Answer
Q. Absorption of Tetracycline is reduced in the presence of milk because of
a. Hydrogen bonding
b. Protein binding
c. Ionization
d. Chelation
Q. Functional groups of same valance and ring equivalents are known as
a. Classical Bioisosteres
b. Non- Classical Bioisosteres
c. Enantiomer
d. Geometric isomer
Q. Bioisosteres have
a. Same physical properties
b. Same chemical properties
c. Similar biological properties
d. All of above
Q. (+) Sotalol is beta blocker while (-) Sotalol is
a. beta blocker
b. Analgesic
c. Antidepressant
d. Antiarrhythmic
Q. D-Penicillamine is antiarthritic while L-Penicillamine is
a. Antiarthritic
b. Antiarrhythmic
c. Antidepressant
d. Toxic
Q. D-Asparagine has sweet taste while L-Asparagine has
a. Sweet taste
b. Sour Taste
c. Bitter Taste
d. Tasteless
Q. Biotransformation of drugs is defined as the conversion from one physical form toanother.
a. True
b. False
c. none
d. all
Q. Following are the Phase I reactions except ____________
a. Oxidative reactions
b. Hydrolytic reactions
c. Reductive reactions
d. Sulphide reactions
Q. Which of the following statements is the closest description of Phase I metabolism?
a. Reactions which add a polar molecule to a functional group already present on a drug or one of its metabolites
b. Reactions which occur in the blood supply.
c. Reactions which add a polar functional group to a drug.
d. Reactions which occur in the gut wall.