Top 350+ Solved Biopharmaceutics and Pharmacokinetics MCQ Questions Answer
Q. Primary binding site for albumin is ………………binding site.
a. Warfarin
b. Diazepam
c. Digitoxin
d. Tamoxifen
Q. Which of the following strategies are widely used to improve or promote transport of drug to brain?
a. Glycosylation
b. Use of Mannitol
c. Prodrug approach
d. All of the above
Q. Protein binding ……………the distribution of drugs.
a. Decreases
b. Increases
c. No Change
d. none of the above
Q. Which one of the following physicochemical property is more important for passive diffusion of drugs from the GIT?
a. Partition coefficient
b. Lipid solubility
c. pH of GIT fluids
d. dissolution constant
Q. Drug permeation through BBB can be improved by………..
a. Glycosylation
b. Mannitol
c. Dihydropyridine redox system
d. all of the above
Q. Which of the following drug diffuses readily into the brain?
a. Penicillin
b. Thiopental
c. Dopamine
d. all of the above
Q. Drug distribution in an organ depends on…………
a. Organ size
b. Perfusion rate
c. Partition Coefficient
d. all of the above
Q. Protein binding of acidic drugs decreased in………..
a. Trauma
b. Surgery
c. Hepatic Cirrhosis
d. Burns
Q. Which one of the following sentences will be the actual definition of distribution?
a. Transfer of drug from the administration dosage to surrounding fluid
b. Transfer of drug from the surrounding the fluid to the blood
c. Transfer of the drug from the oral cavity to the intestine
d. Reversible tr
Q. What should be the molecular weight of the drug molecules so that they can easily pass through the membrane?
a. 600-800 Dalton
b. 500-600 Dalton
c. 300-500 Dalton
d. 200-400 Dalton
Q. Which type of drug cannot enter the cell membrane in the below picture?
a. Ionized drug
b. Unionized drug
c. Hydrolyzed drug
d. Unhydrated drug