Top 350+ Solved Biopharmaceutics and Pharmacokinetics MCQ Questions Answer
Q. Which of the following is used in solvent deposition method of enhancing bioavailability?
a. Freeze drying
b. Organic solvent
c. Inorganic clays like bentonite
d. Creating metastable polymorphs
Q. Which of the following is used in solid solutions method of enhancing bioavailability?
a. Highly water-soluble compound
b. Organic solvent
c. Inorganic clays like bentonite
d. Creating metastable polymorphs
Q. Which of the following is used in molecular encapsulation of drugs for enhancing bioavailability?
a. Highly water-soluble compound
b. Cyclodextrin
c. Inorganic clays like bentonite
d. Creating metastable polymorphs
Q. What is bioequivalence?
a. Comparison between 3-year-old drugs to the same new drug
b. Comparison between a drugs to another drug
c. Comparison between a drug’s specific characteristics to a defined set of standards
d. Comparison between two or 3 characteristics of a drug to the same characteristics of a different drug
Q. What is the chemical equivalence?
a. Two or more drug products contain the same labeled chemical substance in the same amount
b. Two or more drug products contain the same labeled chemical substance in different quantity
c. Two or more drug products contain different labeled chemical substance giving the same therapeutic effect
d. Two or more drug products contain the same labeled chemical substance giving a different therapeutic effect
Q. What is pharmaceutic equivalence?
a. Two or more drug products contain the same labeled chemical substance in the same amount
b. Two or more drug products are identical in quality, purity, uniformity, disintegration, dissolution
c. Two or more drug products contain different labeled chemical substance giving the same therapeutic effect
d. Two or more drug products contain the same labeled chemical substance giving a different therapeutic effect
Q. What is bioequivalence?
a. Drug substance reaches the systemic circulation at the same rate in two or more identical dosage
b. Two or more drug products contain the same labeled chemical substance in different quantity
c. Two or more drug products contain different labeled chemical substance giving the same therapeutic effect
d. Two or more drug products contain the same labeled chemical substance giving a different therapeutic effect
Q. What is therapeutic equivalence?
a. Two or more drug products contain the same labeled chemical substance in the same amount
b. Two or more drug products contain the same labeled chemical substance in different quantity
c. Two or more drug products contain the same labeled chemical substance giving the same therapeutic effect
d. Two or more drug products contain the same labeled chemical substance giving a different therapeutic effect
Q. On which individuals study of newly invented medicines are not done?
a. Pregnant and elderly
b. Fasting person
c. Healthy person
d. Adult male
Q. What should be the disadvantage of cross over study on volunteers?
a. Minimize the intersubject variability in plasma drug levels
b. Minimize the carry-over effect
c. Minimizes variations due to time effect
d. Takes a lot of time to get the result of the study
Q. If the bioavailability of test formulation is 80-120% of the reference standard, it is considered to bebioequivalent.
a. True
b. False
c. none
d. all
Q. The concentration of drug in plasma above which toxic effects are precipitated is known as
a. Maximum safe concentration
b. Minimum Effective Concentration
c. Intensity of Action
d. Duration of Action
Q. When rate is independent of the reactant concentration, then it is called
a. zero order reaction
b. Pseudo zero order reaction
c. First order reaction
d. Second order reaction