Top 350+ Solved Biopharmaceutics and Pharmacokinetics MCQ Questions Answer
Q. Which of the following is not an important parameter of plasma level time studies?
a. Cmax
b. Tax
c. The area under the plasma level-time curve
d. Steady state level
Q. The urinary excretion of the unchanged drug is directly proportional to the plasma concentration of adrug.
a. True
b. False
c. none
d. all
Q. Which of the following will not be a parameter that should be examined for urinary excretion data?
a. (dXu/dt) max
b. (tu)max
c. Xu
d. Cmax
Q. Which of the following is not measured in acute pharmacological response study?
a. ECG
b. EEG
c. Pupil diameter
d. Serum drug level
Q. Therapeutic response is based on observing the clinical response to a drug formulation.
a. True
b. False
c. none
d. all
Q. In vitro determination of bioavailability by dissolution rate is not the best way to determinetherapeutic efficacy.
a. True
b. False
c. none
d. all
Q. The time period for which the plasma concentration of drug remains above minimum effective concentration is known as ______________
a. Onset of time
b. Onset of action
c. Duration of drug of action
d. Therapeutic range
Q. Which of the following is not an approach for overcoming bioavailability problems?
a. Pharmaceutic approach
b. Pharmacokinetic approach
c. Biologic approach
d. Partition coefficient approach
Q. What will be the particle size after micronization of drugs?
a. 1-10 micron
b. 10-20 micron
c. 20-30 micron
d. 1-5 micron
Q. What is the principle behind the use of surfactants?
a. Reducing the size of solid drug particles
b. Enhancing the dissolution rate by promoting wetting
c. Improving solubility
d. Alter the pH of the microenvironment
Q. How pH alteration of the drug microenvironment is done?
a. Altering the pH while the administration
b. In situ salt formation
c. Altering the pH of the tissue
d. Formulating the drug in such a way that it gets activated only when it reaches the tissue pH
Q. Which one of the following is used for selective adsorption on insoluble carriers of the drugs?
a. Freeze drying
b. Organic solvent
c. Inorganic clays like bentonite
d. Creating metastable polymorphs