Top 150+ Solved Pharmaceutical Chemistry - Medicinal Chemistry 4 MCQ Questions Answer
Q. Propranolol is used in hyperthyroidism:
a. As short-term symptomatic therapy till effect of carbimazole develops
b. As long-term therapy after subtotal thyroidectomy
c. In patients not responding to carbimazole
d. To potentiate the effect of radioactive iodine
Q. Action of Insulin does not include the following:
a. Facilitation of glucose transport into cells
b. Facilitation of glycogen synthesis by liver
c. Facilitation of neoglucogenesis by liver
d. Inhibition of lipolysis in adipose tissue
Q. The major limitation of the thiazolidinediones in the treatment of type 2 diabetes mellitus is:
a. Frequent hypoglycaemic episodes
b. Hyperinsulinemia
c. Lactic acidosis
d. Low hypoglycaemic efficacy in moderate to severe cases
Q. Glucose entry into the cells of the following organ/tissue is highly dependent on the presence ofinsulin:
a. Brain
b. Liver
c. Adipose tissue
d. Kidney tubules
Q. Clofibrate is synthesized from
a. o-chloro phenol
b. m-chloro phenol
c. p-chloro phenol
d. 3,4, -dichloro phenol
Q. 6-Chloro-3,4-dihydro-2H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide is IUPAC name of
a. Hydrochlorthiazide
b. Acetazolamide
c. Furosemide
d. Ethacrinic acid
Q. Hydrazine hydrate is precursor for synthesis of
a. Hydrochlorthiazide
b. Acetazolamide
c. Furosemide
d. Ethacrinic acid
Q. IUPAC name of given drug is
a. Benzoic acid, 5- (aminosulphonyl)-4-chloro-2-[(2-furanyl 1-methyl) amino]
b. Benzoic acid, 3- (aminosulphonyl)-4-chloro-2-[(2-furanyl 1-methyl) amino]
c. Benzoic acid, 5- (aminosulphonyl)-3-chloro-2-[(2-furanyl 1-methyl) amino]
d. Benzoic acid, 3- (aminosulphonyl)-3-chloro-2-[(2-furanyl 1-methyl) amino]
Q. The structure of steroids is based on the ____________________skeleton.
a. 1,2-cyclopentanophenanthrene
b. 1,2-cyclohexanophenanthrene
c. 1,3-cyclopentanophenanthrene
d. 1,3-cyclohexanophenanthrene
Q. 2-(2,3-dichlorophenoxy acetic acid) and butyryl chloride are precursors for synthesis of
a. Hydrochlorthiazide
b. Acetazolamide
c. Furosemide
d. Ethacrinic acid