Top 150+ Solved Pharmaceutical Chemistry - Medicinal Chemistry 4 MCQ Questions Answer
Q. Activity of cardiac glycoside depends to a great extent on
a. 23rd carbonyl oxygen
b. C – 3 OH
c. Side chain at C – 14
d. Side chain at C – 17
Q. Angiotensin II causes rise in blood pressure by:
a. Direct vasoconstriction
b. Releasing adrenaline from adrenal medulla
c. Increasing central sympathetic tone
d. All of the above
Q. Digitalis slows the heart in congestive heart failure by:
a. Increasing vagal tone
b. Decreasing sympathetic overactivity
c. Direct depression of sinoatrial node
d. All of the above
Q. Losartan is
a. Renin release blocker
b. ACE inhibitor
c. Angiotension I blocker
d. Angiotension II blocker
Q. IUPAC name of Dobutamine is
a. 4-(2-{[4-(4-hydroxyphenyl)butan-2-yl]amino}ethyl)benzene-1,2-diol
b. 4-(2-{[4-(4-hydroxyphenyl)butan-2-yl]amino}methyl)benzene-1,2-diol
c. 4-(2-{[4-(4-hydroxyphenyl)propan-2-yl]amino}ethyl)benzene-1,2-diol
d. 4-(2-{[4-(4-hydroxyphenyl) propan -2-yl]amino}methyl)benzene-1,2-diol
Q. 1-[4-(2-methoxyethyl)phenoxy]-3-[(propan-2-yl)amino]propan-2-ol is IUPAC name of
a. Atenolol
b. Metoprolol
c. Captopril
d. Hydralazine
Q. Hydralazine is synthesized from
a. 2-formyl benzoic acid and Hydrazine
b. Methacrylic acid
c. 2-azidoethanol
d. o-nitro toluene
Q. The principal action common to all class I antiarrhythmic drugs is:
a. Na+ channel blockade
b. K+ channel opening
c. Depression of impulse conduction
d. Prolongation of effective refractory period
Q. _____________ is carboxylic acid moiety containing.
a. Captopril
b. Enalapril
c. Fosinopril
d. Bepridil
Q. _____________ is sulfhydryl moiety containing.
a. Captopril
b. Enalapril
c. Fosinopril
d. Bepridil
Q. The antiarrhythmic drug which decreases both rate of depolarization (phase 0) as well as rate of repolarization (phase 3) of myocardial fibres is:
a. Lignocaine
b. Propranolol
c. Quinidine
d. Verapamil
Q. The following drug is used to reduce the frequency of angina pectoris as well as to terminate an acute attack:
a. Isosorbide dinitrate
b. Pentaerythritol tetranitrate
c. Diltiazem
d. Dipyridamole