Top 80+ Solved Bioavailability and Bioequivalence MCQ Questions Answer
Q. Which of the following is not an approach for overcoming bioavailability problems?
a. Pharmaceutic approach
b. Pharmacokinetic approach
c. Biologic approach
d. Partition coefficient approach
Q. What will be the particle size after micronization of drugs?
a. 1-10 micron
b. 10-20 micron
c. 20-30 micron
d. 1-5 micron
Q. What is the principle behind the use of surfactants?
a. Reducing the size of solid drug particles
b. Enhancing the dissolution rate by promoting wetting
c. Improving solubility
d. Alter the pH of the microenvironment
Q. How pH alteration of the drug microenvironment is done?
a. Altering the pH while the administration
b. In situ salt formation
c. Altering the pH of the tissue
d. Formulating the drug in such a way that it gets activated only when it reaches the tissue pH
Q. Which one of the following is used for selective adsorption on insoluble carriers of the drugs?
a. Freeze drying
b. Organic solvent
c. Inorganic clays like bentonite
d. Creating metastable polymorphs
Q. Which of the following is used in solvent deposition method of enhancing bioavailability?
a. Freeze drying
b. Organic solvent
c. Inorganic clays like bentonite
d. Creating metastable polymorphs
Q. Which of the following is used in solid solutions method of enhancing bioavailability?
a. Highly water-soluble compound
b. Organic solvent
c. Inorganic clays like bentonite
d. Creating metastable polymorphs
Q. Which of the following is used in molecular encapsulation of drugs for enhancing bioavailability?
a. Highly water-soluble compound
b. Cyclodextrin
c. Inorganic clays like bentonite
d. Creating metastable polymorphs
Q. What is bioequivalence?
a. Comparison between 3-year-old drugs to the same new drug
b. Comparison between a drugs to another drug
c. Comparison between a drug’s specific characteristics to a defined set of standards
d. Comparison between two or 3 characteristics of a drug to the same characteristics of a different drug
Q. What is the chemical equivalence?
a. Two or more drug products contain the same labeled chemical substance in the same amount
b. Two or more drug products contain the same labeled chemical substance in different quantity
c. Two or more drug products contain different labeled chemical substance giving the same therapeutic effect
d. Two or more drug products contain the same labeled chemical substance giving a different therapeutic effect
Q. What is pharmaceutic equivalence?
a. Two or more drug products contain the same labeled chemical substance in the same amount
b. Two or more drug products are identical in quality, purity, uniformity, disintegration, dissolution
c. Two or more drug products contain different labeled chemical substance giving the same therapeutic effect
d. Two or more drug products contain the same labeled chemical substance giving a different therapeutic effect
Q. What is bioequivalence?
a. Drug substance reaches the systemic circulation at the same rate in two or more identical dosage
b. Two or more drug products contain the same labeled chemical substance in different quantity
c. Two or more drug products contain different labeled chemical substance giving the same therapeutic effect
d. Two or more drug products contain the same labeled chemical substance giving a different therapeutic effect
Q. What is therapeutic equivalence?
a. Two or more drug products contain the same labeled chemical substance in the same amount
b. Two or more drug products contain the same labeled chemical substance in different quantity
c. Two or more drug products contain the same labeled chemical substance giving the same therapeutic effect
d. Two or more drug products contain the same labeled chemical substance giving a different therapeutic effect
Q. On which individuals study of newly invented medicines are not done?
a. Pregnant and elderly
b. Fasting person
c. Healthy person
d. Adult male