Top 80+ Solved Bioavailability and Bioequivalence MCQ Questions Answer
Q. Comparison of the rate and extent of the absorption of drug from the formulation under study to thedata of a reference standard that is given intravenously is known as:
a. Biopharmaceutics
b. Relative bioavailability
c. Absolute bioavailability
d. Bioavailability
Q. If the Relative Bioavailability is 1, it indicates:
a. Bioavailability of dosage form of one drug is same as that of the other dosage form
b. Complete binding of the drugs to the proteins as compared to the standard drug
c. Complete bioavailability of the drug
d. Complete distribution of the drug
Q. What would be the order of greater or lesser bioavailability of the dosage forms?
a. Intravenous > rectal > oral > topical
b. Intravenous > oral > rectal > topical
c. Intravenous > topical > rectal > oral
d. Oral > intravenous > rectal > topical
Q. The term bioavailability refers to the………….
a. relationship between the physical and chemical properties of a drug and the systemic absorption of the drug
b. measurement of the rate and amount of therapeutically active drug that reaches the systemic circulation
c. movement of drug into the body tissues over time
d. dissolution of a drug in the gastrointestinal tract
Q. The reasons determining bioavailability are…..
a. Rheological parameters of blood
b. Amount of a substance obtained orally and quantity of intakes
c. Extent of absorption and hepatic first-pass effect
d. Glomerular filtration rate
Q. Bioavailability is defined as…..
a. Rate of drug absorption
b. Rate of drug distribution
c. Rate of drug elimination
d. Rate and extent of absorption
Q. The rate of drug bioavailability is most rapid when the drug is formulated as a…..
a. controlled released product
b. hard gelatin capsule
c. tablet
d. solution
Q. The drug concentration between MEC and MSC represents the….
a. Therapeutic Index
b. Therapeutic range
c. Therapeutic outcome
d. Therapeutic ratio
Q. Dissolution test apparatus I as per IP is…..
a. Paddle
b. Basket
c. Rotating basket
d. Rotating paddle
Q. Non-invasive measurement of drug concentration includes ……….sampling.
a. hair
b. urine
c. saliva
d. All of the above
Q. Ex-vivo models refer to…….
a. in the body
b. in the computer
c. outside the body
d. none of the above
Q. USP dissolution test apparatus type-II is also called as…..
a. Hansen paddle type
b. paddle over disc
c. Rotating basket type
d. none of the above
Q. Bioavailability of drug from topical administration is affected by…..
a. Skin condition
b. Topical vehicle
c. Application condition
d. all of the above