Top 80+ Solved Bioavailability and Bioequivalence MCQ Questions Answer
Q. What is bioavailability?
a. The time of absorption of the drug from its dosage form
b. The rate of absorption of the unchanged drug from its dosage form
c. The time of absorption of the unchanged drug from its dosage form
d. The rate of absorption of the drug from its dosage form
Q. What is the equation of bioavailable fraction?
a. 1/Bioavailable dose
b. 1/Administered dose
c. Bioavailable dose/Administered dose
d. Administered dose/Bioavailable dose
Q. Which of the following is not an objective of bioavailability studies?
a. Primary stages of development of suitable dosage form for new drug
b. Determination of the influence of excipients, patient-related factors, etc
c. Development of new formulations of the existing drugs
d. Control the quantity of the drug to be administered
Q. Multiple dose study is better since we can understand the peak, valley, drug blood levels, etc.
a. True
b. False
c. none
d. all
Q. Which of the following is the pharmacodynamics method of studying bioavailability?
a. Acute pharmacologic response
b. Plasma-level time studies
c. Urinary excretion studies
d. Stool excretion studies
Q. Which of the following is not an important parameter of plasma level time studies?
a. Cmax
b. Tax
c. The area under the plasma level-time curve
d. Steady state level
Q. The urinary excretion of the unchanged drug is directly proportional to the plasma concentration of adrug.
a. True
b. False
c. none
d. all
Q. Which of the following will not be a parameter that should be examined for urinary excretion data?
a. (dXu/dt) max
b. (tu)max
c. Xu
d. Cmax
Q. Which of the following is not measured in acute pharmacological response study?
a. ECG
b. EEG
c. Pupil diameter
d. Serum drug level
Q. Therapeutic response is based on observing the clinical response to a drug formulation.
a. True
b. False
c. none
d. all
Q. In vitro determination of bioavailability by dissolution rate is not the best way to determinetherapeutic efficacy.
a. True
b. False
c. none
d. all
Q. The time period for which the plasma concentration of drug remains above minimum effective concentration is known as ______________
a. Onset of time
b. Onset of action
c. Duration of drug of action
d. Therapeutic range