Top 50+ Solved Protein Binding of Drugs MCQ Questions Answer
Q. Which one of the following bonds is not generally a bond through which a drug will bind in our body?
a. Hydrogen bond
b. Hydrophobic bond
c. Ionic bond
d. Covalent bond
Q. Binding of drugs falls into 2 components those are _______________
a. Binding of drugs to blood components and to extravascular tissue
b. Binding of drugs to blood components and to other cells
c. Binding of drugs to cells and blood cells
d. Binding of drugs to blood components to bones and cells
Q. Which one of the following is the correct order of the drugs binding to various plasma protein?
a. Albumin > alpha-1 acid glycoprotein > globulins > lipoproteins
b. Albumin > globulins > lipoproteins > alpha-1 acid glycoprotein
c. Albumin > alpha-1 acid glycoprotein > lipoproteins > globulins
d. Albumin > lipoproteins > globulins > alpha-1 acid glycoprotein
Q. Which vitamin molecules will bind to alpha 2 globulin?
a. Vitamin b complexes
b. Vitamin a and vitamin b
c. Vitamin A, D, E, K
d. Steroids bind to alpha 2 globulin, not vitamin
Q. What is the molecular weight of human serum albumin?
a. 5000 Dalton
b. 65,000 Dalton
c. 60,000 Dalton
d. 75,000 Dalton
Q. What is the name of the drug binding site I of HSA?
a. Tamoxifen binding site
b. Digitoxin binding site
c. Diazepam binding site
d. Warfarin and azapropazone binding site
Q. Which one of the below does not belong to the 4 classes of lipoprotein?
a. Chylomicrons
b. Very low-density lipoproteins
c. High-density lipoprotein
d. Fatty acids
Q. What is the name of the drug binding site IV of HSA?
a. Tamoxifen binding site
b. Digitoxin binding site
c. Diazepam binding site
d. Warfarin and azapropazone binding site
Q. Acidic drugs like imipramine, lidocaine bind to alpha 1 Acid Glycoprotein.
a. True
b. False
c. none
d. all
Q. What is the name of the drug binding site III of HSA?
a. Tamoxifen binding site
b. Digitoxin binding site
c. Diazepam binding site
d. Warfarin and azapropazone binding site
Q. What is the name of the drug binding site II of HSA?
a. Tamoxifen binding site
b. Digitoxin binding site
c. Diazepam binding site
d. Warfarin and azapropazone binding site
Q. Which one of the following factors related to protein-drug binding is not related to drugs?
a. Physicochemical characteristics of a drug
b. The concentration of the drug in the body
c. The affinity of the drug for binding
d. Number of binding sites on the binding agent
Q. Which one of the following factor related to protein-drug binding is not related to drug interactions with the binding site?
a. Competition between the drug and the binding site
b. Competition between drugs and normal body constituents
c. Allosteric changes in a protein molecule
d. Inter subject variation