Top 350+ Solved Biopharmaceutics and Pharmacokinetics MCQ Questions Answer
Q. Which drug accumulate in adipose tissue?
a. Arsenicals
b. Tetracycline
c. Halogenated hydrocarbons
d. Lipophilic drug
Q. Which drugs results in distortion of double stranded DNA structure?
a. Arsenicals
b. Quinacrine
c. Halogenated hydrocarbons
d. Lipophilic drug
Q. In equation X=Vd C, what does Vd denotes?
a. Density
b. Volume of blood
c. Volume of body
d. The volume of the body fluid in which the drug is getting dissolved
Q. The amount of drug in the body is directly proportional to the concentration of the drug in plasma.
a. True
b. False
c. none
d. all
Q. The body water has 3 distinct compartments. Which one of these is not one of the compartments?
a. Vascular fluid
b. Intracellular fluid
c. Extracellular fluid
d. Between the tissue layers
Q. How can you determine the extracellular fluid volume?
a. Evans blue
b. Na+
c. D20
d. Tritiated water
Q. The total body water volume can be determined by using high molecular weight dyes.
a. True
b. False
c. none
d. all
Q. How will you determine the intracellular fluid volume?
a. Evans blue
b. Na+
c. Difference between total body water and ECF volume
d. Tritiated water
Q. What will be the apparent volume of distribution of warfarin?
a. The apparent volume of distribution is less than the true volume of distribution
b. The apparent volume of distribution is more than the true volume of distribution
c. The apparent volume of distribution is equal to the true volume of distribution
d. Warfarin is not a medicine
Q. What will bet the apparent volume of distribution of drugs which binds selectively to extravascular tissues?
a. The apparent volume of distribution is less than the true volume of distribution
b. The apparent volume of distribution is more than the true volume of distribution
c. The apparent volume of distribution is equal to the true volume of distribution
d. The apparent volume of distribution is equal to the volume of extravascular tissues
Q. Which one of the following bonds is not generally a bond through which a drug will bind in our body?
a. Hydrogen bond
b. Hydrophobic bond
c. Ionic bond
d. Covalent bond
Q. Binding of drugs falls into 2 components those are _______________
a. Binding of drugs to blood components and to extravascular tissue
b. Binding of drugs to blood components and to other cells
c. Binding of drugs to cells and blood cells
d. Binding of drugs to blood components to bones and cells
Q. Which one of the following is the correct order of the drugs binding to various plasma protein?
a. Albumin > alpha-1 acid glycoprotein > globulins > lipoproteins
b. Albumin > globulins > lipoproteins > alpha-1 acid glycoprotein
c. Albumin > alpha-1 acid glycoprotein > lipoproteins > globulins
d. Albumin > lipoproteins > globulins > alpha-1 acid glycoprotein