Top 350+ Solved Biopharmaceutics and Pharmacokinetics MCQ Questions Answer

From 346 to 360 of 389

Q. Which organs comprise the central compartment in a two compartment model?

a. Muscles

b. Skin

c. Adipose

d. Liver

  • d. Liver

Q. Which organ comprises the peripheral compartment in a two compartment model?

a. Liver

b. Lungs

c. Kidneys

d. Muscles

  • d. Muscles

Q. Which of the following is not a category of 2 compartment model?

a. Two compartment model with elimination from the central compartment

b. Two compartment model with elimination from the peripheral compartment

c. Two compartment model with elimination from only plasma and blood

d. Two compartment model with elimination from both the compartments

  • d. Two compartment model with elimination from both the compartments

Q. Non-linear pharmacokinetics is also known as………

a. dose dependent

b. enzyme capacity limited

c. saturation pharmacokinetics

d. All of the above

  • d. All of the above

Q. The characteristic of non-linear pharmacokinetics include…………..

a. Area under the curve is proportional to the dose

b. Elimination half-life remains constant

c. Area under the curve is not proportional to the dose

d. Amount of drug excreted through remains constant

  • c. Area under the curve is not proportional to the dose

Q. Which of following drug shows non-linearity in hepatic excretion?

a. Carbamazepine

b. Propranolol

c. Penicillin

d. Thiopental

  • a. Carbamazepine

Q. Pharmacokinetics parameters change as per………… of dose administered?

a. Size

b. Route

c. Both of free above

d. None of the above

  • a. Size

Q. Linear Pharmacokinetics is………………

a. Dose dependent

b. Dose independent

c. Both of the above

d. None of the above

  • a. Dose dependent

Q. Non-linear Pharmacokinetics also called as…………

a. Mixed order

b. Saturated kinetics

c. Capacity Limited

d. All of the above

  • d. All of the above

Q. In…………..Pharmacokinetic parameters for a drug can change with change in dose.

a. Linear Pharmacokinetics

b. Non-linear Pharmacokinetics

c. Both of the above

d. None of the above

  • b. Non-linear Pharmacokinetics

Q. The………………….. is common cause of both dose and time dependent kinetics

a. Capacity limited Process

b. Dose volume

c. Enzyme induction

d. None of the above

  • c. Enzyme induction

Q. When Km << C. In this condition…………..

a. Km – C = C

b. Km + C = C

c. Km + C = Km

d. Km - C = Km

  • b. Km + C = C

Q. Active processes which are Saturable in renal excretion of drug includes…….

a. Active tubular secretion

b. Active tubular reabsorption

c. Both of the above

d. None of the above

  • c. Both of the above

Q. Linear Pharmacokinetics also referred as………….

a. First-order kinetics

b. Second order kinetics

c. Pseudo order kinetics

d. None of the above in

  • a. First-order kinetics

Q. If the steady-state plasma concentration is directly proportional to the dose, then ……….in thekinetics exists.

a. Linearity

b. Non-linearity

c. Both of the above

d. None of the above

  • a. Linearity
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