Top 350+ Solved Biopharmaceutics and Pharmacokinetics MCQ Questions Answer
Q. This is the equation for the calculation of creatinine clearance. Which age group does the Clcr = 0.48 H / Scr *[W/70]0.7 formula belong to?
a. 1-6 years
b. 1-20 years
c. Males above 20 years
d. Females above 20 years
Q. This is the equation for the calculation of creatinine clearance. Which age group does the Clcr = (140 – Age) W / 72 * Scr formula belong to?
a. 1-6 years
b. 1-20 years
c. Males above 20 years
d. Females above 20 years
Q. This is the equation for the calculation of creatinine clearance. Which age group does the Clcr = (140 – Age) W / 85 * Scr formula belong to?
a. 1-6 years
b. 1-20 years
c. Males above 20 years
d. Females above 20 years
Q. A girl with age 21 has height 240cm, weight 55kg, serum creatinine of 0.8mg will have ______________ creatinine clearance.
a. 80 ml/min
b. 90 ml/min
c. 96.25 ml/min
d. 85 ml/min
Q. An adult male with age 22 has height 240cm, weight 85kg, serum creatinine of 0.8mg will have ______________ creatinine clearance.
a. 150 ml/min
b. 160 ml/min
c. 170.13 ml/min
d. 174.131 ml/min
Q. Which creatinine clearance value shows moderate renal failure?
a. 120-130 ml/min
b. 20-50 ml/min
c. Below 10 ml/min
d. 70-80 ml/min
Q. Which creatinine clearance value shows severe renal failure?
a. 120-130 ml/min
b. 20-50 ml/min
c. Below 10 ml/min
d. 70-80 ml/min
Q. Drugs in patients with renal impairment have same pharmacokinetic profile as in a person withoutrenal failure.
a. True
b. False
c. none
d. all
Q. Which kind of membrane is used in haemodialysis?
a. Artificial Semipermeable membrane
b. Permeable membrane
c. Natural semipermeable membrane of the peritoneal cavity
d. Artificial permeable membrane
Q. Which kind of membrane is used in haemodialysis?
a. Artificial Semipermeable membrane
b. Permeable membrane
c. Natural semipermeable membrane of peritoneal cavity
d. Artificial permeable membrane
Q. Which of the following will not be a factor governing the removal of substances through dialysis?
a. Molecular weight
b. Water solubility
c. Disintegration time
d. Protein binding
Q. Which of the following is not a mechanism for pharmacokinetic analysis?
a. Compartment analysis
b. Non compartment analysis
c. Physiologic modeling
d. Human model
Q. In which of the following models the body is considered to be composed of several compartments?
a. Compartment model
b. Noncompartment model
c. Physiologic model
d. Human model
Q. In which of the model peripheral compartments are connected to a central compartment?
a. Compartment model
b. Caternary model
c. Physiologic model
d. Mammillary model