Top 250+ Solved Absorption MCQ Questions Answer
Q. Based on Henderson-Hasselbalch equation, at what pH value a weak acid would be 99.9% ionized?
a. At pH equivalent to pKa - 3
b. At pH equivalent to pKa + 3
c. At pH equivalent to pKa – 1
d. At pH equivalent to pKa + 1
Q. In passive diffusion, the transport of drugs takes place from a region of ……………concentration to a ……………..concentration.
a. Lower, Higher
b. Higher, Lower
c. Both (a) and (b)
d. none of the above
Q. Which is the major process of absorption for more than 90% of drugs?
a. Facilitated diffusion
b. Active transport
c. Endocytosis
d. Passive diffusion
Q. What is the driving force for Passive Diffusion?
a. Concentration gradient only
b. Electrochemical gradient only
c. Charge equilibration and concentration gradient
d. Concentration and Electrochemical gradient both
Q. Which kind of molecules cannot pass through a pore transport?
a. Low Molecular weight molecules
b. Water-soluble drugs
c. Molecules up to 400 Dalton
d. Molecules greater than 400 Dalton
Q. What is the driving force of Pore Transport?
a. Hydrostatic pressure
b. Concertation Gradient
c. Electrochemical gradient
d. Charge equilibration
Q. What will be the best definition for “carrier”?
a. Nonpolar drugs can be transported through carrier-mediated transport
b. Carrier binds reversibly and no covalently with the molecules
c. It discharges the molecules and gets destroyed itself
d. The carrier is a protein
Q. What is the major difference between Facilitated diffusion and Passive diffusion?
a. Carrier-mediated transport
b. Downhill transport
c. Energy is used
d. Inhibition by metabolic poisons
Q. What influences the permeation of drugs in an Ionic or Electrochemical diffusion?
a. Charge on the membrane
b. Charge on the particle
c. Concentration gradient
d. Equilibration of charge
Q. Which kind of drugs are absorbed through endocytosis?
a. Molecular weight ranging 100-400Dalton
b. Water-soluble drugs
c. Macromolecular drugs or drugs as oily droplets
d. Polar drugs
Q. Which drugs are absorbed through pore transport?
a. High lipophilicity
b. Water-soluble drugs of molecular weight less than 100 Dalton
c. Oily droplets
d. Affinity for carriers
Q. Which types of drugs get absorbed by ion-pair transport?
a. High lipophilicity
b. Oily droplets
c. Affinity for carriers
d. Drugs that ionize at all pH conditions
Q. Which of these absorption methods involves engulfing of the extracellular drug?
a. Endocytosis
b. Passive diffusion
c. Facilitated diffusion
d. Ion-Pair tr
Q. Which is the other name of “cell eating”?
a. Transcytosis
b. Phagocytosis
c. Pinocytosis
d. Endocytosis
Q. Transfer of an endocytic vesicle from one extracellular compartment to another is known as
a. Phagocytosis
b. Transcytosis
c. Pinocytosis
d. Endocytosis