Top 250+ Solved Absorption MCQ Questions Answer
Q. The rate of diffusion of drug across biological membrane is
a. Directly proportional to the concentration gradients
b. Dependant on route of administration
c. Indirectly proportional to membrane thickness
d. None of the above
Q. Absorption of griseofulvin is……………
a. Dissolution rate limited
b. Permeation rate limited
c. Perfusion rate limited
d. None of the above
Q. Micronized form of drug absorbed fast because
a. surface area increased
b. viscosity increased
c. angle of distribution increased
d. none of the above
Q. …………form of weakly acidic drug absorbed well in stomach
a. ionized
b. unionised
c. both
d. none of the above
Q. Which of the following forms inclusion complex and improves aqueous solubility and dissolution rate?
a. Cyclodextrins
b. PEG
c. PVT
d. Poloxamer
Q. According to pH partition theory, a weak acidic drug will most likely be absorbed from the stomachbecause the drug which exist primarily in the
a. Unionized, more lipid soluble form
b. Ionised, more water soluble form
c. Form of weak acid and more soluble in acid media
d. Ionic form of the drug, which facilitates diffusion
Q. Very weak bases having pKa < 5
a. Are ionized in the entire pH range of GIT
b. Show absorption, which is pH dependent
c. Are unionized at all pH values
d. None of the above
Q. IV route of drug administration does not involve…………
a. distribution step
b. absorption step
c. biotransformation step
d. All of the above
Q. In carrier mediated transport energy is derived from……..
a. Hydrolysis of ATP
b. Protein metabolism
c. Concentration gradient
d. All of the above
Q. Which of the following drug is not stable in the gastric fluid?
a. Erythromycin
b. Paracetamol
c. Salicylic acid
d. none of the above
Q. ………types of drugs are absorbed by pore transport mechanism.
a. Macromolecules
b. Ionic drugs
c. Drugs with molecular weight 100-400
d. Water soluble drugs of molecular weight less than 100
Q. Area in which the carrier system is most dense is called as…………..
a. Therapeutic window
b. Absorption index
c. Therapeutic index
d. Absorption window
Q. Which of the following is carrier mediated transport system
a. passive diffusion
b. active transport
c. pore transport
d. none of the above
Q. Absorption of poorly soluble drug is
a. diffusion rate limited
b. dissolution rate limited
c. both (a) & (b)
d. none of the above
Q. Which of the following process drug moves from site of administration to systemic circulation?
a. excretion
b. absorption
c. distribution
d. metabolism