Top 550+ Solved Physiology MCQ Questions Answer

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Q. Diffusion is inversely proportional to:

a. the diffusion constant

b. tissue area

c. solubility of the gas

d. square root of the molecular weight

e. the difference in partial pressure

  • d. square root of the molecular weight

Q. In exercise:

a. oxygen consumption is about 6L/min in a moderately fit subject

b. the respiratory exchange ratio rises to 0.8

c. diffusing capacity increases 3-fold

d. the change in cardiac output is only about a sixth of the increase in ventilation

e. the oxygen dissociation curve moves to the left

  • c. diffusing capacity increases 3-fold

Q. Central respiratory chemoreceptors:

a. are located in the medulla near exit of cranial nerve X, XI

b. respond directly to changes in external PCO2

c. respond directly to changes in arterial PO2

d. are located on dorsal surface of medulla

e. respond to pH of CSF

  • e. respond to pH of CSF

Q. Respiratory peripheral chemoreceptors:

a. carotid bodies respond to PO2, PCO2, and pH

b. peripheral chemoreceptor response to arterial PCO2 is more important than central chemoreceptor response

c. aortic bodies are located within the aortic valve ring

d. drop in PO2 < 100mmHg causes increase in firing rate

e. carotid bodies respond to venous PO2

  • d. drop in PO2 < 100mmHg causes increase in firing rate

Q. Ventilatory response to CO2 is reduced by all EXCEPT:

a. sleep

b. barbiturate overdose

c. increasing age

d. decreasing the work of breathing

e. trained athletes and divers

  • d. decreasing the work of breathing

Q. The surface area of the lungs is:

a. three times the area of skin

b. ten times the area of skin

c. 30 times the area of skin

d. 100 times the area of skin

e. none of the above

  • c. 30 times the area of skin

Q. Site of most / major airway resistance is:

a. trachea

b. main bronchi

c. large bronchi

d. medium sized bronchi

e. bronchioles

  • d. medium sized bronchi

Q. The volume of the anatomical dead space is:

a. 50mL

b. 100mL

c. 150mL

d. 200ml

e. 300ml

  • c. 150mL

Q. Which respiratory volume is INCORRECT?

a. tidal volume is the normal breathing volume

b. vital capacity is the volume from maximal inspiration followed by maximal expiration

c. residual volume is the volume remaining in lungs after maximal expiration

d. functional residual capacity is the volume after normal inspiration

e. total lung capacity is the vital capacity plus residual volume

  • d. functional residual capacity is the volume after normal inspiration

Q. The diffusion constant is proportional to:

a. tissue thickness

b. square root of the molecular weight

c. difference in partial pressures

d. tissue area

e. gas solubility

  • e. gas solubility

Q. Mean pressure (mmHg) in the main pulmonary artery is:

a. 2

b. 5

c. 8

d. 15

e. 25

  • d. 15

Q. Regarding pulmonary blood flow:

a. increased arterial pressure leads to increased pulmonary vascular resistance

b. localised vasoconstriction is directly due to arterial PO2 hypoxia

c. regional differences are due to hydrostatic pressure differences

d. at the apex Pa>Pv>PA

e. pulmonary arteries and veins have transmural pressures equal to alveolar pressure

  • c. regional differences are due to hydrostatic pressure differences

Q. Which is not inactivated by the lungs?

a. serotonin

b. bradykinin

c. leukotrienes

d. prostaglandin E2

e. vasopressin

  • e. vasopressin

Q. Regarding the alveolar gas equation:

a. the respiratory quotient nears 1.0 with exercise

b. PIO2= barometric pressure – water vapour pressure

c. PACO2 > PaCO2

d. PAO2 is normally 150mmHg

e. remains valid if there is CO2 present in the inspired gas

  • a. the respiratory quotient nears 1.0 with exercise

Q. The amount of O2 in blood with a PaO2 of 100mmHg is:

a. 0.003ml O2/100ml

b. 0.3ml O2/100ml

c. 3ml O2/100ml

d. 3ml O2/mL

e. 0.3ml O2/L

  • b. 0.3ml O2/100ml
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