Top 550+ Solved Physiology MCQ Questions Answer
Q. Regarding mitochondria, which of the following is TRUE?
a. 99% of mitochondrial proteins are products of mitochondrial DNA
b. the outer membrane of the mitochondria is folded to form cristae
c. the space between the outer and inner mitochondrial space is called matrix space
d. it is the sperm which contributes to the formation of mitochondria in the zygote
e. the synthesis of ATP in the mitochondria is triggered by diffusion of H+ from matrix to intracristal space
Q. Which is FALSE?
a. fast fibres have small number of mitochondria
b. fast fibres are called white muscles
c. the glycolic processes are more important in energy supply in fast fibres
d. slow fibres are also called red fibres
e. fast fibres have more extensive blood supply than slow fibres
Q. Smooth muscles differ from skeletal muscle by:
a. not having actin/myosin
b. not having striated appearance
c. not using ATP for contraction
d. not using Ca2+ for contraction
e. not having sarcoplasmic reticulum
Q. Which of the following is absent in smooth muscle?
a. tropomysin
b. actin
c. myosin
d. troponin
e. mitochondria
Q. The highest number of voltage gated Na+ channels are found in:
a. initial segment of axon
b. nodes of Ranvier
c. cell body
d. terminal buttons
e. myeline sheath
Q. Which of the following is most susceptible to pressure?
a. group A – motor
b. group C
c. group B
d. pre ganglionic-autonomic
e. muscle spindle fibres
Q. Regarding nerve action potential, which is TRUE?
a. normal resting membrane potential is -40mV
b. initial rapid depolarisation is due to rapid influx of Ca2+ via fast channels
c. during depolarisation, Na+ permeality is greater than K+ permeality
d. hyperpolarisation is due to continuous opening of Na+ channels
e. plateau is formed by slow Ca2+ channels
Q. Which is FALSE regarding secondary active transport?
a. it always transports substances in one direction
b. energy required is obtained by Na+ /K+ ATPase pump
c. a good example is Na+ / glucose co-transport
d. Na+ / Ca2+ antiport is an example of secondary active transport
e. secondary active transport occurs in renal tubules
Q. Na+ / K+ ATPase pump – which is FALSE?
a. it is electrogenic in nature
b. it is important in maintaining cell volume
c. plays a major role in secondary active transport
d. it is the main factor which determine the resting membrane potential
e. it is an example of primary active transport
Q. Regarding serotonin:
a. the highest concentration is in the brain
b. formed by hydroxylation and decarboxylation of tyrosine
c. catabolised by COMT
d. some receptors are ion channels
e. mediates smooth muscle relaxation
Q. Which is NOT present in high concentrations, at the active zone of synapses?
a. syntaxin
b. catecholamine vesicles
c. neuropeptide vesicles
d. synaptobrevin
e. calcium channels
Q. Which is not a ligand-gated ion channel?
a. nicotinic receptor
b. GABAA receptor
c. glycine receptor
d. NMDA receptor
e. 5-HT1 receptor
Q. Which drug is NOT involved in facilitating Cl- conductance?
a. benzodiazepines
b. progesterone
c. oestrogen
d. barbiturates
e. alcohol
Q. Regarding skeletal muscle:
a. isotonic contraction does no work
b. calcium is released from troponin during contraction
c. the resting membrane potential is -70mV
d. treppe occurs in skeletal muscle only
e. white muscle has short twitch durations
Q. Regarding smooth muscle:
a. tropomyosin is absent
b. the resting membrane potential is -90mV
c. there is a highly developed sarcoplasmic reticulum
d. there are no spike potentials
e. dense bodies are attached to the cell membrane