Top 150+ Solved Pathology MCQ Questions Answer
Q. In apoptosis
a. It involves physiologic and pathologic stimuli
b. Histologically, it involves coagulation necrosis
c. Its DNA breakdown is random and diffuse
d. Its mechanism involves ATP depletion
e. It involves an inflammatory tissue reaction
Q. Hyperplasia
a. Occurs after partial hepatectomy
b. Refers to an increase in the size of cells
c. Is always a pathologic process
d. Often occurs in cardiac and skeletal muscle
e. Usually progresses to cancerous proliferation
Q. Metastatic calcification
a. Causes widespread tissue damage
b. Occurs with normal calcium levels
c. Can be caused by systemic sarcoidosis
d. Occurs in hypothyroidism
e. Is caused by drinking large quantities of milk
Q. Prothrombotic characteristics of endothelium include
a. Plasminogen activator
b. Prostacyclin
c. von Willebrand factor
d. Thrombomodulin
e. Heparin like molecules
Q. Regarding giant cell arteritis, which statement is not correct
a. Affects medium arteries
b. Affects small arteries including vertebral
c. Affects small arteries including ophthalmic
d. Has an increased prevalence of HLA-DR4
e. Has no gastrointestinal manifestations
Q. All of the following organisms cause a clinical effect via the production of an exotoxin except
a. Clostridium tetani
b. Staphylococcus aureus
c. E. coli
d. Pseudomonas aerugenosa
e. Vibrio cholera
Q. Select the true statement concerning atherosclerosis
a. Congenital absence of LDL cholesterol leads to premature atherosclerosis
b. Thoracic aorta is more likely to be involved than the abdominal
c. Fatty streaks appear in the aortas of children as young as 1 year
d. Fatty streaks are destined to become atherosclerotic plaques
e. Endothelial disruption always precedes atheroma development
Q. Select the false statement concerning atherosclerosis
a. Familial hypercholesterolaemia is associated with inadequate hepatic uptake of LDL
b. CMV has been detected in human atheromatous plaques
c. Fibrous atheromatous plaques are capable of regression
d. Foam cells can be considered to be specialised macrophages
e. Atherosclerosis is associated with medial calcific sclerosis
Q. An infectious complication of transfusion
a. Is most commonly Hepatitis C
b. Is most commonly Hepatitis B
c. Is rarely transmission of HIV since screening was instituted
d. Never includes gonorrhoea or malaria
e. Can be clinically apparent mononucleosis in about 7% of cases
Q. Which of the following is true concerning rhabdomyolysis
a. It is caused by injury to smooth muscle
b. Its diagnosis depends on the presence of characteristic physical findings
c. The final common pathway of injury involves damage to the sarcolemma
d. Renal failure is due to acute glomerular nephritis
e. Occurs only in trauma
Q. Neutrophilia is generally caused by all of the following except
a. Inflammatory disease
b. Bacterial infection
c. Viral infection
d. Corticosteroids
e. Stress
Q. Which of the following is true of chronic myeloid leukaemia
a. Most common leukaemia
b. Decreased leukocyte alkaline phosphatase level
c. Usually occurs in patients less than 40 years old
d. Increased WBC count with an abnormal differential
e. Rarely associated with the Philadelphia chromosome
Q. All of the following are cardiac compensatory responses that occur in heart failure except
a. Cardiac muscle fibre stretching
b. Increased adrenergic receptors on cardiac cells
c. Chamber hypertrophy
d. Decreased heart rate
e. Increased vasopressin levels
Q. Shock in burn patients is primarily due to
a. Neurogenic factors
b. Hypovolaemia
c. Acute erythrocyte haemolysis
d. Myocardial depression factor
e. All of the above