Top 150+ Solved Nervous System MCQ Questions Answer
Q. Regarding the structure of cardiac muscle, which statement is INCORRECT?
a. T-system lies at Z-lines
b. functions as a syncytium due to the presence of tight junctions
c. intercalated discs occur at Z-lines
d. contains large numbers of elongated mitochondria
e. thin filaments include troponin T, C and I
Q. Regarding the cardiac muscle action potential, which statement is INCORRECT?
a. sodium ions enter via “fast” channels in phase 0
b. chloride ions may enter cell during phase 1
c. sodium ions enter via “slow” channels in phase 2
d. relative refractory period ends in phase 3
e. class I anti-arrhythmics reduce the slope of phase 4
Q. Which of the following nerve fibre types represents the efferent limb of the musclespindle reflex arc?
a. A-alpha
b. A-beta
c. A-gamma
d. A-delta
e. B
Q. Regarding neuromuscular transmission, which statement is INCORRECT?
a. smooth muscle cells possess synapses en passant
b. about 10 times as much acetylcholine as is required is released at skeletal muscle neuromuscular junctions
c. antibodies can develop to calcium channels in nerve endings at neuromuscular junctions
d. more than one nerve fibre ends on each end-plate in skeletal muscle
e. acetylcholine is released by exocytosis
Q. Regarding the structure of skeletal muscle, which statement is INCORRECT?
a. thick filaments consist of myosin
b. actin forms a double helix
c. thin filaments include tropomyosin
d. troponin-I inhibits interaction between actin and myosin
e. T-system lies at Z-lines
Q. Which of the following nerve fibre types has the fastest conduction velocity?
a. B
b. A-delta
c. A-beta
d. A-gamma
e. C
Q. Regarding the nerve fibre action potential, which statement is INCORRECT?
a. does not involve calcium ions
b. after-depolarisation commences when repolarisation is 70% complete
c. total number of ions involved is minute compared to the total number present
d. spike potential peaks at sodium equilibrium potential
e. firing level (threshold) is at about -55mV
Q. Which of the following nerve fibre types is MOST sensitive to local anaestheticblockade?
a. A-alpha
b. A-gamma
c. A-delta
d. B
e. C
Q. Regarding neurotoxins, which statement is INCORRECT?
a. tetrodotoxin is a sodium channel blocker
b. tetraethylammonium is a potassium channel blocker
c. tetanospasmin interferes with GABA release
d. botulinum toxin blocks release of acetylcholine
e. latrotoxin causes explosive release of acetylcholine
Q. Regarding conduction of nerve impulses, which statement is INCORRECT?
a. it is an active, self-propagating process
b. salutatory conduction occurs in unmyelinated neurons
c. axons can conduct impulses in either direction
d. conduction velocity is proportional to nerve fibre diameter
e. “current sink” occurs in neuronal cell membrane ahead of impulse
Q. B nerve fibres transmit impulses of which modality?
a. proprioception
b. preganglionic autonomic
c. temperature
d. postganglionic sympathetic
e. somatic motor
Q. Regarding nerve fibres, which statement is INCORRECT?
a. resting membrane potential is about -90mV
b. action potentials are generated at the initial segment in spinal motor neurons
c. myelin produces up to 50 times faster conduction of impulses
d. membrane is more permeable to potassium than sodium at rest
e. sodium channels are highly concentrated at the nodes of ranvier
Q. Regarding skeletal muscle, which statement is INCORRECT?
a. resting membrane potential is about -90mV
b. resting length is the length at which active tension in the muscle is maximal
c. total glycogen stored is about 0.4kg
d. energy source at rest is mainly glucose
e. resting heat production is due to basal metabolic processes
Q. Which of the following nerve fibre types has the LEAST myelin?
a. A-alpha
b. A-beta
c. A-gamma
d. B
e. C
Q. A-alpha nerve fibres transmit impulses of which modality?
a. proprioception
b. pain
c. pressure
d. touch
e. motor to muscle spindles