Top 80+ Solved Cardiovascular MCQ Questions Answer
Q. The depolarisation of cardiac muscle cells is characterised by:
a. a slow depolarisation, a plateau then a rapid repolarisation
b. initial depolarisation due to a slow Na+ influx
c. repolarisation due to K+ efflux through two types of K+ channels
d. a plateau phase due to slowly opening Na+ channels
e. calcium efflux during the plateau phase
Q. Regarding cardiac electrical properties:
a. all cardiac cells have the same resting membrane potential
b. cholinergic fibres act predominantly by blocking tonic sympathetic input
c. discharge rates of pacemaker tissue does not change significantly with temperature
d. the bundle of HIS is not the most rapidly conducting part of the conducting system
e. the last parts of myocardium to depolarise normally do not include the septum
Q. Abnormalities causing ECG changes in myocardial infarction include:
a. delayed repolarisation early on
b. delayed depolarisation
c. increased resting membrane potential
d. TQ segment elevation
e. current flow away from the infarct
Q. Features of the venous system include all of the following EXCEPT:
a. total volume is approximately 55% of the total vascular volume
b. compliance approximately 25 times the arterial side
c. total volume of venules is twice the total capillary volume
d. valves in the cerebral circulation
e. substantial venoconstriction in response to noradrenaline
Q. Regarding the inputs into the vasomotor centre:
a. baroreceptors causes stimulation
b. chemoreceptors cause inhibition
c. baroreceptors provide significant input below 70mmhg mean arterial pressure
d. atrial stretch receptors inhibit the vasomotor centre
e. direct inputs include pO2
Q. CSF:
a. volume is about 600ml
b. normal pressure is 5-10cm CSF
c. has a higher concentration of creatinine than plasma
d. has a higher concentration of urea than plasma
e. is formed solely in the choroid plexus
Q. Regarding the conduction system of the heart:
a. the right bundle branch (of HIS) divides into anterior and posterior fasicles
b. the AV node contains P cells
c. myocardial fibres have a resting membrane potential of -60mV
d. action potential in the SA and AV nodes are largely due to Na+ influx
e. there are two types of K+ channels in pacemaker tissue – transient and long acting
Q. During systole:
a. the peak left ventricular pressure is 160mmHg
b. contraction of the atria propels 70% of the ventricular filling
c. the period of isovolumetric ventricular contraction is 0.5sec????
d. the end systolic ventricular volume is about 50mL
e. coronary blood flow to subendocardial portions of the left ventricle occur only in systole
Q. Regarding cardiac output:
a. “energy of contraction is proportional to the initial length of the cardiac muscle fibre” is Fick’s Law of the heart
b. cardiac index is the correlation between resting cardiac output and height
c. sleep decreases cardiac output
d. basal O2 consumption by the myocardium is 2ml/g/min
e. standing normally decreases the length of ventricular cardiac muscle fibres
Q. Effects of electrolyte changes:
a. PR interval increases in hyperkalaemia
b. in hyperkalaemia, the heart stops in systole
c. hypercalcaemia causes prolongation of the ST segments
d. hypernatraemia is associated with low voltage electrocardiographic complexes
e. magnesium counteracts digitalis toxicity
Q. Which statement is TRUE regarding cardiac muscle?
a. cardiac muscle fibres are multinucleated
b. they are smaller than skeletal muscle fibres
c. Ca2+ release is triggered by membrane repolarisation
d. the elastic ‘Titin” protein component is greater than in skeletal muscle, adding stiffness
e. the amount of Ca2+ in the sarcoplasmic reticulum is decreased by catecholamine stimulation
Q. Which statement regarding cardiac “work” is FALSE?
a. the energy applied to the blood stream is defined as kinetic plus potential
b. potential energy involves consideration of energy stored in elastic arterial walls and gravity
c. there is an exchange between kinetic and potential energy
d. the largest drop in energy occurs at the level of the precupillary sphincters
e. the higher resistance in smaller calibre vessels corresponds to greater energy losses
Q. Which statement about blood flow is FALSE?
a. cardiac output = stroke volume x heart rate
b. the volume of blood pumped through the lungs equals the volume entering the heart
c. Poiseville’s Law predicts the effects of pressure and resistance on cardiac output
d. the resistance of the systemic circulation is 5 to 10 times the pulmonary vascular resistance
e. with constant pressure, a vessel with radius ‘2X ‘ has 16 times the flow of vessel with radius ‘X’
Q. Regarding haemodynamic principles, which statement is FALSE?
a. viscosity of blood with haematocrit of 40 is three times that of water
b. ‘arterial’ blood volume is 10-15% total volume
c. ‘elastance’ measures a vessel’s stiffness or recoil
d. aging causes increased elastance and therefore decrease in resting (unstressed) arterial volume
e. an increase in total peripheral resistance leads to increased arterial volume and BP