Top 550+ Solved Physiology MCQ Questions Answer
Q. Regarding brown fat, which of the following is TRUE?
a. it is fat with a large percentage of melatonin as a constituent
b. it has extensive parasympathetic innervation
c. it is more abundant in adults than in infants
d. heat production is assisted by uncoupling of the H+ /ATP generator system in mitochondria
e. brown fat cells contain multiple droplets of fat
Q. Regarding thyroid hormones, which statement is INCORRECT?
a. thyroid hormones bind to receptors in cell nuclei
b. T3 is less potent than T4
c. thyroid hormones increase O2 consumption
d. T3 promotes nitrogen excretion
e. cerebral glucose consumption is increased by thyroid hormones
Q. Regarding the respiratory quotient, which of the following is TRUE?
a. it is the ratio of CO2 produced to the volume of O2 consumed per unit of time
b. is related to tidal volume
c. is inversely proportioned to pO2
d. has a value of 2.3 for fats
e. varies with age
Q. Which of the following statements is INCORRECT?
a. in a low protein diet, nitrogen excretion by the kidney decreases
b. in a low protein diet, the maximal urine osmolarity is decreased
c. there is a net negative nitrogen balance following the administration of steroids
d. nitrogen balance becomes negative if a single amino acid is missing from the diet
e. insulin spares the breakdown of muscle protein
Q. Which of the following is an ESSENTIAL fatty acid?
a. myristic acid
b. palmitic acid
c. stearic acid
d. linolenic acid
e. oleic acid
Q. Regarding protein metabolism in starvation, which statement is INCORRECT?
a. glucose has a protein sparing effect by increasing insulin secretion
b. death occurs when protein depletion reaches 50% of normal level
c. total starvation leads to loss of up to 5gms/day of urea nitrogen due to protein catabolism
d. most protein catabolised comes from the liver, spleen and skeletal muscles
e. rapid protein depletion is the terminal phase once fat stores have been almost totally catabolised
Q. Which of the following is NOT an unsaturated fatty acid?
a. oleic acid
b. arachidonic acid
c. linoleic acid
d. linolenic acid
e. stearic acid
Q. Regarding brown fat, which statement is INCORRECT?
a. fat cells have extensive parasympathetic innervation
b. responsible for part of the post-prandial heat production
c. fat cells contain several droplets of fat
d. prominent between and around the scapulae of infants
e. fat cells contain many mitochondria
Q. Regarding carbohydrate metabolism in starvation, which statement is INCORRECT?
a. hepatic glycogenolysis precedes skeletal muscle glycogenolysis
b. blood glucose falls less in women due to greater fat stores
c. glycogen stores are exhausted after half to one day
d. blood glucose level is maintained above a level that would produce symptomatic hypoglycaemia
e. skeletal muscle contains about four times as much glycogen as the liver
Q. Regarding lipoproteins, which statement is INCORRECT?
a. VLDL transport cholesterol formed in liver to extrahepatic tissues
b. chylomicrons can cause post-prandial plasma to appear milky
c. LDL are taken up by macrophages
d. oestrogens increase plasma HDL levels
e. elevated IDL levels predispose to atherosclerosis
Q. Which of the following does NOT increase the activity of intracellular hormonesensitive lipase?
a. GH
b. PGE
c. thyroxine
d. glucagon
e. cortisol
Q. Which of the following causes a positive nitrogen balance?
a. increased cortisol secretion
b. starvation
c. decreased insulin secretion
d. forced immobilisation
e. increased testosterone secretion
Q. Which statement regarding lipoprotein lipase is INCORRECT?
a. it is not hormone sensitive
b. it requires heparin as a co-factor
c. it is confined to adipose tissue
d. its activity is decreased by stress
e. it clears chylomicrons and VLDL from circulation by degradation of triglyceride
Q. Regarding uric acid, which statement is INCORRECT?
a. the majority of filtered uric acid is reabsorbed in the proximal tubule
b. xanthine oxidase catalyses its synthesis
c. may be elevated in leukaemia and pre-eclampsia
d. does not undergo renal tubular secretion
e. its excretion rate can be halved by changing to a purine-free diet
Q. Regarding ketone bodies, which statement is INCORRECT?
a. formed following ingestion of a high fat/low carbohydrate diet
b. acetoacetate and beta-hydroxybutyrate formation leads to a metabolic acidosis
c. acetone is excreted in the urine
d. readily metabolised by the liver
e. acetone formation leads to ketotic breath