Top 150+ Solved Pharmacology MCQ Questions Answer

a. Penetrates the axon in its changed form

b. Is more potent than bupivacaine

c. Has higher affinity for activated than resting sodium channels

d. Is a weak acid

e. Blocks voltage gated sodium channels at their extracellular end

a. Post op vomiting is common

b. Hypertension is a complication

c. Severe acidosis can occur with its use in paediatric respiratory infections

d. It is positively inotropic

e. Tremor is a common side effect

a. They reduce MAP in direct proportion to their alveolar concentration

b. Nitrous oxide has a relatively low MAC

c. Halogenated agents have a lower brain:blood partition coefficient

d. Nitrous oxide causes a decrease in tidal volume and an increase in respiratory rate

e. They decrease the metabolic rate in the brain by decreasing cerebral blood flow

a. Are primarily K+ channel blockers

b. Prevent repolarisation of the membrane

c. Can be used with a vasodilator to prolong local action

d. Activity is enhanced by high extracellular K+ concentration

e. Activity is enhanced by high extracellular Ca2+

a. Phenytoin – gum hypertrophy

b. Ethosuximide – hirsuitism

c. Phenobarbital – enzyme induction

d. Carbamazepine – ataxia

e. Valproate – idiosyncratic hepatic toxicity

a. Miosis

b. Confusion

c. Diarrhoea

d. GIT haemorrhage

e. Bronchorrhoea

a. Is not lipid soluble

b. Can be used IM or IV to induce anaesthesia

c. Has good analgesic properties

d. Can cause convulsive movements

e. Anaesthetic action is terminated by redistribution from CNS to other highly vascularised tissues

a. Can be used with O2 as a carrier gas for halothane

b. Has poor analgesic properties

c. Forms a vapour which is explosive

d. Sensitises the heart to the action of catecholamines

e. Is an effective agent for inducing anaesthesia

a. Is more potent than fentanyl

b. Frequently causes diarrhoea

c. Is used to treat nausea caused by morphine

d. Occurs in foxglove plants

e. Depresses the cough reflex

a. Receptor blockers have anticonvulsant activity

b. Is found in high concentrations in the basal ganglia

c. Concentrations in the basal ganglia are abnormally low in Huntington’s chorea

d. Metabolism is inhibited by sodium valproate

e. Receptors are sensitive to the activity of benzodiazepines

a. Lignocaine is metabolised in the liver faster than any of the other amide LA

b. Allergies to amide Las are more common than with the ester Las

c. Prilocaine is the most cardiotoxic LA

d. Cocaine is an amide LA which is often used as a drug of abuse

e. The +1/2 of lignocaine may be increased 3-4 fold in a patient with severe liver disease

a. Jaw and eye muscles are paralysed before the limb and trunk muscles

b. Rocuronium is the most potent nondepolarising skeletal muscle relaxant

c. Atracurium is a steroid derivative

d. Vecuronium blocks cardiac muscarinic receptors, thus inducing moderate increase in heart rate

e. The nondepolarising agents produce a non-surmountable blockade

a. Suxamethonium

b. Mivacurium

c. Pancuronium

d. Rocuronium

e. Vecuronium

a. Small diameter

b. Myelination

c. Location in the periphery of a nerve

d. High firing rate

e. Short action potential duration

a. Work to lower BP initially by decreasing peripheral vascular resistance

b. Thiazide diuretics are potassium sparing

c. Are effective in lowering Bp by 20 – 25 mmHg in most patients

d. BP response to thiazides continues to increase at doses greater than usual therapeutic dose.

e. Diuretics may impair glucose tolerance