Top 50+ Solved CNS Drugs MCQ Questions Answer

a. Metabolites are important to the action of these drugs

b. Haloperidol has a higher systemic availability than thioridazine or chlorpromazine

c. Elimination half lives of these drugs range between 3 – 6 hours

d. This group of drugs generally has short clinical duration of action

e. Clozipine is a member of the dihydroindolone group

a. Chlorpromazine

b. Clozapine

c. Thioridazine

d. Haloperidol

e. Thiothixene

a. Pregnancy

b. Use of thiazides

c. Dehydration

d. Use of some non-steroidal anti-inflammatory drugs

e. Post partum state

a. Most are highly protein bound

b. Fluoxetine is poorly absorbed

c. Tricyclics are predominantly excreted unchanged in the urine

d. Plasma half lives of antidepressants are mostly less than 10 hours

e. The half life of the older MAOIs is helpful in governing doses

a. Moclobemide

b. Paroxetine

c. Sertraline

d. Trazodone

e. Amoxapine

a. Gentamicin

b. Theophylline

c. Carbamazepine

d. Atenolol

e. Diazepam

a. Zolpidem

b. Chloral hydrate

c. Buspirone

d. Phenobarbitone

e. Diazepam

a. Lignocaine is also an antiarrhythmic of the Vaughan Williams classification group 1A

b. At normal pH the larger fraction of local anaesthetic in the body fluids will be in the unchanged form

c. Bupivacaine may cause an apparent cyanosis in some patients

d. The duration of action of procaine will be increased in the presence of liver disease

e. Local anaesthetic agents block conduction in small myelinated axons prior to blockade of other axons

a. Ketamine is the induction agent of choice in a head injured patient

b. Propofol has a slow offset of action

c. Etomidate causes hypotension more commonly than thiopentone

d. Ideal agents for neuroleptanalgesia are fentanyl and droperidol

e. Thiopentone is metabolised at a rate of 40-50% per hour in humans following a single dose

a. Is a non-depolarising neuromuscular blocking agent

b. Is contraindicated in all eye operations

c. Stimulates cardiac muscarinic receptors and autonomic ganglia

d. Its action is directly terminated by the action of plasma cholinesterase

e. Should not be administered to patients with burns >24 hours old because of its hypercalcaemic effect

a. Enflurane is proconvulsant

b. Isoflurane is the inhalational agent of choice in patients with active IHD

c. Nitrous oxide is a useful adjunct to volatile anaesthetic use in women in the first trimester of pregnancy

d. Halothane has a MAC value of 75% making it less potent than desflurane

e. Desflurane is extensively metabolised via the liver

a. Is 20-30% bound to albumin

b. Is the drug treatment of choice in absence seizures

c. Undergoes flow limited elimination

d. Steady state mean plasma concentrations varies disproportionately with the dose

e. Preferentially binds to activated state sodium channels

a. Ketamine is structurally related to psilocybin

b. LSD acts on various 5 HT receptor subtypes to produce its mind altering effects

c. Marijuana causes mydriasis and conjunctival infection

d. Cocaine has a long plasma half life

e. Amphetamine like drugs cause marked stimulation of appetite

a. Is cleared renally

b. Predictably reverses benzodiazepine induced respiratory depression

c. Antagonises CNS effects of opioids

d. Can precipitate seizures in mixed overdose

e. Has a half life of around 10 hours

a. Pancuronium is eliminated via the kidney

b. Roacuronium is an isoquinolone derivative

c. Roacuronium undergoes Hoffman elimination

d. Vecuronium is eliminated predominantly via the kidney

e. Atracurium is eliminated via plasma pseudocholinesterase