Q. Thiazide diuretics enhance K+ elimination in urine primarily by: (Solved)

1. Inhibiting proximal tubular K+ reabsorption

2. Inhibiting Na+ K+-2Cl– cotransport in the ascending limb of loop of Henle

3. Increasing the availability of Na+ in the distal tubular fluid to exchange with interstitial K+

4. Potentiating the action of aldosterone

  • c. Increasing the availability of Na+ in the distal tubular fluid to exchange with interstitial K+
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