Q. Diuretics acting on the ascending limb of loop of Henle are the most efficacious in promotingsalt and water excretion because: (Solved)

1. Maximum percentage of salt and water is reabsorbed in this segment

2. Reabsorptive capacity of the segments distal to it is limited

3. This segment is highly permeable to both salt and water

4. This segment is responsible for creating corticomedullary osmotic gradient

  • b. Reabsorptive capacity of the segments distal to it is limited
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