Q. The ACE inhibitors (Solved)

1. Inhibit peptidyl dipeptidase thus preventing the inactivation of bradykinin

2. Captopril is a prodrug

3. Are to be used with caution in patients with IHD as reflex sympathetic activation occurs secondary to the hypotensive effects of the ACE inhibitors

4. Have no role in treating the normotensive diabetic patients

5. Are useful antihypertensive agents in late pregnancy