Q. Regarding the “azole” group of antifungals (Solved)
1. Fluconazole has low water solubility
2. Ketoconazole may be given IV/PO
3. Itraconazole undergoes renal elimination
4. Clotrimazole is the treatment of choice for systemic candidiasis – given orally
5. They work by reduction of ergosterol synthesis by inhibition of fungal cytochrome P450 enzymes
- e. They work by reduction of ergosterol synthesis by inhibition of fungal cytochrome P450 enzymes