Q. Pharmacokinetics of doxycycline (Solved)

1. 20% bound by serum proteins

2. 60-70% absorption after oral administration

3. Absorption is impaired by divalent cations, Al3+, and antacids

4. Widely distributed especially into the CSF

5. Is eliminated via renal mechanisms

  • c. Absorption is impaired by divalent cations, Al3+, and antacids
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