Q. Which of the following drugs cause diuresis by the mechanisms indicated? (Solved)

1. Ethanol – by preventing the reabsorption of sodium from renal tubular fluid

2. Digoxin – by inhibiting release of ADH

3. Dopamine – by inhibiting active transport of chloride over the entire length of the descending limb of the loop of Henle

4. Frusemide – by inhibiting carbonic anhydrase

5. Chlorothiazide – by inhibiting active sodium transport in the ascending limb of the loop of Henle