Top 250+ Solved Respiration MCQ Questions Answer

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Q. Regarding surfactant:

a. infant respiratory distress syndrome can be adequately treated with administration of phospholipids alone

b. cigarette smokers have the same amount of surfactant as non-smokers

c. the phospholipid film is formed by tubular myelin

d. infant respiratory distress syndrome is caused by insufficient surfactant that prevents the alveoli from expanding at first inspiratory effort

e. formation of the phospholipid film is greatly facilitated by the carbohydrate in surfactant

  • c. the phospholipid film is formed by tubular myelin

Q. Regarding the work of breathing during quiet inspiration:

a. elastic work = 80%

b. viscous resistance = 7%

c. airway resistance = 13%

d. when tidal volume versus intrapleural pressure in quiet inspiration are plotted, a straight line results

e. the amount of elastic work required to inflate the whole respiratory system is more than the amount required to inflate the lungs alone

  • b. viscous resistance = 7%

Q. Regarding gas exchange in the lungs:

a. N2O is diffusion limited

b. CO is perfusion limited

c. O2 is between N2O and CO but at rest, is perfusion limited

d. diffusing capacity of the lung for a gas is inversely proportionate to the surface area of the alveolocapillary membrane and directly proportional to its thickness

e. at rest, it takes blood 0.25secs to traverse the pulmonary capillaries

  • c. O2 is between N2O and CO but at rest, is perfusion limited

Q. Regarding bronchial tone:

a. substance P causes bronchoconstriction

b. constriction is caused by sympathetic discharge

c. dilation is caused by parasympathetic discharge

d. maximal bronchoconstriction occurs at 4am

e. VIP causes bronchoconstriction

  • a. substance P causes bronchoconstriction

Q. Regarding pulmonary function, which of the following is NOT true?

a. FRC = ERV + RV

b. IRV in men is about 3,3L

c. RV in women is about 1.1L

d. inspiratory capacity in men = 4.8L

e. total lung capacity = 6L in men, 4.2L in women

  • d. inspiratory capacity in men = 4.8L

Q. Regarding the glottis:

a. when laryngeal adductors are paralysed there is inspiratory stridor

b. abductors contract early in inspiration

c. when abductors are paralysed, aspiration pneumonia may result

d. the adductors are supplied by the vagus nerves, the abduction by the hypoglossal nerve

e. in animals with bilateral cervical vagotomy, pulmonary oedema is purely secondary to aspiration

  • b. abductors contract early in inspiration

Q. Regarding the O2 dissociation curve:

a. O2 affinity of Hb is reduced when the curve is shifted to the left

b. decreased 2,3-DPG shifts the curve to the right

c. the Bohr effect is attributed to the action of PCO2 on H+ concentration

d. temperature has no effect on the curve

e. 2,3-DPG levels are reduced at altitude

  • c. the Bohr effect is attributed to the action of PCO2 on H+ concentration

Q. Diffusion is inversely proportional to:

a. the diffusion constant

b. tissue area

c. solubility of the gas

d. square root of the molecular weight

e. the difference in partial pressure

  • d. square root of the molecular weight

Q. In exercise:

a. oxygen consumption is about 6L/min in a moderately fit subject

b. the respiratory exchange ratio rises to 0.8

c. diffusing capacity increases 3-fold

d. the change in cardiac output is only about a sixth of the increase in ventilation

e. the oxygen dissociation curve moves to the left

  • c. diffusing capacity increases 3-fold

Q. Central respiratory chemoreceptors:

a. are located in the medulla near exit of cranial nerve X, XI

b. respond directly to changes in external PCO2

c. respond directly to changes in arterial PO2

d. are located on dorsal surface of medulla

e. respond to pH of CSF

  • e. respond to pH of CSF

Q. Respiratory peripheral chemoreceptors:

a. carotid bodies respond to PO2, PCO2, and pH

b. peripheral chemoreceptor response to arterial PCO2 is more important than central chemoreceptor response

c. aortic bodies are located within the aortic valve ring

d. drop in PO2 < 100mmHg causes increase in firing rate

e. carotid bodies respond to venous PO2

  • d. drop in PO2 < 100mmHg causes increase in firing rate

Q. Ventilatory response to CO2 is reduced by all EXCEPT:

a. sleep

b. barbiturate overdose

c. increasing age

d. decreasing the work of breathing

e. trained athletes and divers

  • d. decreasing the work of breathing

Q. The surface area of the lungs is:

a. three times the area of skin

b. ten times the area of skin

c. 30 times the area of skin

d. 100 times the area of skin

e. none of the above

  • c. 30 times the area of skin

Q. Site of most / major airway resistance is:

a. trachea

b. main bronchi

c. large bronchi

d. medium sized bronchi

e. bronchioles

  • d. medium sized bronchi

Q. The volume of the anatomical dead space is:

a. 50mL

b. 100mL

c. 150mL

d. 200ml

e. 300ml

  • c. 150mL
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