Top 50+ Solved Endocrinology MCQ Questions Answer
Q. Which is not a potential etiology of hypoglycemia in adults?
a. alcohol
b. salbutamol
c. insulinoma
d. salicylates
e. adrenal insufficiency
Q. Which is the major precipitant of DKA?
a. infection
b. missed doses of insulin
c. AMI
d. Pancreatitis
e. PE
Q. Which is not usually a feature of DKA?
a. seen type 1 diabetics mainly
b. serum osmalality 275-295mmol/l
c. fluid deficit usually less than that in HHNS
d. glucose usually lower than that in HHNS
e. acidosis
Q. Which is not true regarding the management of DKA?
a. the administration of IV fluid immediately on arrival is the life saving event
b. fluid replacement should be 3-4 litres over the first four hours in a pt who is not shocked
c. even if the K+ is >5.5 poatssium replacemnt should be commenced
d. the insulin bolus should be about 0.1 units/kg, with subsequent infusion at 0.1units/kg/hr
e. cerebral oedema responds to mannitol
Q. Which is not a feature of Hyperosmolar, hyperglycemic non ketotic states?
a. very high glucose, often greater than 40 mmol/l
b. ph>7.3
c. serum osmalality often greater than 350 mmol/L
d. low bicarbonate
e. lack of ketones in the urine
Q. Which statement is false about the fluid deficit in HHNS?
a. it is usually 5L
b. if not shocked then 0.45% saline should be given
c. fluid replacement should always precede insulin therapy in the non shocked pt
d. fluid replacement should be done over a longer period of time than in DKA
e. normal saline should be given to the shocked patient
Q. Which is not true about non ketotic hyperosmolar states?
a. these patients usually present with a GCS >8
b. total body potassium is not reduced as in DKA as there is no acidosis
c. focal neurological deficits are sometimes seen
d. they are prone to arterial and vascular thrombosis
e. insulin administration should be at the same rate as in DKA
Q. Which is not true regarding drug therapy in diabetes?
a. the use of ACEI even in normotensive patients, delays the onset of diabetic nephropathy
b. the use of simvistatin in pts with CHD significantly reduces the risk of future CHD
c. sulphonylureas stimulate the pancreatic secretion of insulin
d. Acorbase(Glucobay) interferes with GIT absorption of carbohydrate
e. Metformin is an oral insulin analogue
Q. The nitroprusside dipstick test of the urine measures?
a. acetoacetate
b. beta hydroxybuterate
c. acetone
d. A and C
e. All of the above
Q. Which is not a feature of alcoholic ketoacidosis?
a. Dehydration
b. Positive dipstick for ketones
c. ABG = acidosis, alkalsos or normal
d. Increased anion gap, regardless of pH
e. hyperglycemia
Q. Which is false regarding alcoholic ketoacidosis?
a. it is usually seen in chronic alcoholics
b. usually there has been a recent cessation in drinking with several days of vomiting and poor oral intake
c. Thiamine should be given
d. Mainstay of treatment is IV fluids, including dextrose
e. Low dose insulin given judiciously hastens recovery
Q. Which is the most common precipitant of alcoholic ketoacidosis?
a. pancreatitis
b. GI bleed
c. Alcohol withdrawl without precipitating illness
d. Infection
e. hepatitis
Q. Which may not cause an adrenal crisis?
a. Waterhouse Freidrichson syndrome
b. Sheehans syndrome
c. Acute discontinuation of steroids therapy
d. Anticoagulant use
e. Fulminant septicemia
Q. What biochemical abnormality is possible in an addisonian crisis?
a. hyponatremia
b. hypokalemia
c. hypoglycemia
d. normokalemia and normonatremia
e. all of the above
Q. Which statement is incorrect with regards to treatment of an addisonian crisis?
a. i.v. normal saline should be given to treat shock
b. i.v.dextrose will also be required
c. i.v. fludrocortisone is required
d. i.v. dexamethase or hydrocortisone should be given
e. fluoxymesterone (androgen replacement) does not need to be given