Top 50+ Solved Drug Stability MCQ Questions Answer
Q. For the validity of accelerated stability studies of solution dosage form, the energy of activationshould be in the range of (in units of kcal/mole).
a. 0 to 10
b. 11 to 30
c. 31 to 50
d. 51 to 70
Q. Which one of these methods is the MOST effective in preventing the rate of hydrolysis?
a. buffer
b. complexation
c. removal of water
d. suppression of solubility
Q. During storage, crystal growth is observed in a suspension due to:
a. absorption of water
b. fluctuations in the ambient temperatures
c. presence of suspending agent
d. volatilization of solids
Q. The storage directions on a parenteral solution specify ‘store in a cool place’. This may be stored in:
a. an air-conditioned area at 10°C
b. a refrigerator at 15°C
c. a place whose temperature is set at 5°C
d. room temperature, at 25°C
Q. which of the following is cause of physical degradation of drug?
a. volatilisation of components during storage
b. Changes from one state to another
c. Change in colour
d. All of the above
Q. Which of the following factors affect the rate of reaction?
a. Temperature
b. Catalysis
c. Dielectric constant
d. All of the above
Q. The effect of temperature on rate of reaction is explained by
a. Arrhenius equation
b. Nernst equation
c. Noyes Whitney equation
d. Fick's first law
Q. The dielectric constant is used to measure
a. Viscosity of solvent
b. polarity of the solvent
c. temperature of solvent
d. flowability of solvent
Q. Accelerated stability testing is done to
a. predict shelf of the formulation
b. Predict dissociation constant
c. Predict diffusion constant
d. Determine activation energy
Q. ICH stands for
a. Indian council on harmonisation
b. International Conference On Harmonisation
c. Inter Cranial Healer
d. None of the above
Q. Stability Data for Climatic zone III & IV comes under___________ICH guideline
a. Q1C
b. Q1E
c. Q1F
d. Q1D
Q. Climatic zone II is
a. Moderate climate
b. Subtropical and Mediterranean climate
c. Hot/dry climate
d. Hot/humid climate
Q. Stability testing is done
a. to determine shelf life of product
b. to determine the components used for packaging
c. to get information at preformulation stage
d. All of the above
Q. ........... is the time necessary for the concentration of the reactant to decrease to 90% of its originalconcentration.
a. Product life
b. Shelf life
c. Half life
d. None of the above