Top 150+ Solved Dosage Form Design 2 MCQ Questions Answer
Q. How are OLV liposomes made?
a. 2-10 bilayers of lipid
b. Series of concentric bilayers of lipid
c. A single bilayer of lipid
d. 100 bilayer of lipid
Q. The concentration of drug in plasma above which toxic effects are precipitated is known as
a. Maximum safe concentration
b. Minimum Effective Concentration
c. Intensity of Action
d. Duration of Action
Q. When rate is independent of the reactant concentration, then it is called
a. zero order reaction
b. Pseudo zero order reaction
c. First order reaction
d. Second order reaction
Q. Which of the following is the half life of zero order reaction?
a. t1/2 = A0 /2k
b. t1/2 = 0.693/2k
c. t1/2 = A0 /2
d. t1/2 = 2k/ A0
Q. The unit of k for zero order reaction is
a. moles/litre/second
b. moles
c. moles/second
d. moles/litre
Q. Which of the following is the half life of first order reaction?
a. t1/2 = A0 / 2k
b. t1/2 = 0.693 / 2k
c. tl/2 = 2k
d. tl/2 = 0.693 / k
Q. Which of the following is not a pharmacokinetic parameters that describe the plasma level time curve?
a. tmax
b. cmax
c. Area under Curve
d. Minimum Effective Concentration
Q. The drug concentration between Minimum Effective Concentration and Maximum Safe Concentrationis called
a. Therapeutic range
b. Area under curve
c. Peak response
d. Pharmacological response
Q. tmax indicates
a. drug absorption rate
b. drug elimination rate
c. drug distribution rate
d. drug metabolism rate
Q. What Will be the approximate Tmax of a drug exhibiting Ka of 2 hr-1 and K of 0.2 hr-1 ?
a. 1.2 hr
b. 2.4 hr
c. 4.8 hr
d. 2.0 hr
Q. A drug solution has half life of 21 days. Assuming that drug undergoes first order kinetics, how longwill it take for the potency to drop to 90% of initial potency?
a. 3.2 days
b. 9.6 days
c. 16 days
d. 6.2 days
Q. A suspension shows zero-order kinetic with a rate constant 2mg/ml.month. The dose of suspension is20mg/ml. The biological half life of the above dosage form is
a. 5 months
b. 1 month
c. 3 months
d. 2 months
Q. Drug showing zero order kinetic of elimination
a. Are more common than those showing first order kinetic
b. Show plot of drug concentration vs time (linear Plot)
c. Decrease in concentration exponentially with time
d. Have half life independent of dose
Q. Which one is irrational statement for first order kinetics?
a. Half life is a function of concentration of reactants
b. Reaction rate is not a function of concentration of reactants
c. Both a & b
d. All of these